Evidence map›Paper›PMID 41229184›Full record

ReviewJournal of cosmetic dermatology2025

Safety and Tolerability of the 1440- and 1927-nm Non-Ablative Fractional Diode Laser System for Skin Resurfacing: A Review of Current Literature.

Roy G Geronemus, Jordan V Wang, Abby A Jacobson, Ellen S Marmur, Kristel D Polder

Abstract readReview
In one paragraph

Review in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Roy G GeronemusNew York University Medical Center, New York, New York, USA.ORCID https://orcid.org/0009-0003-9803-8276
Jordan V WangLaser & Skin Surgery Center of Pennsylvania, Devon, Pennsylvania, USA.ORCID https://orcid.org/0000-0001-7437-2745
Abby A JacobsonBausch Health Companies Inc, Bridgewater, New Jersey, USA.ORCID https://orcid.org/0000-0002-7810-2280
Ellen S MarmurMarmur Medical, New York, New York, USA.ORCID https://orcid.org/0000-0002-5612-7807
Kristel D PolderDallas Center for Dermatology and Aesthetics, Dallas, Texas, USA.

Funding

Bausch Health Companies Inc
6 · The paper itself

Abstract

backgroundEnergy-based devices, such as lasers, provide effective treatments for skin resurfacing. Ablative fractional lasers have a higher risk of adverse events (AEs), like scarring and postinflammatory hyperpigmentation, particularly in patients with darker skin types, than non-ablative fractional lasers. The 1440- and 1927-nm non-ablative fractional diode laser (NFDL) system is indicated for use in dermatological procedures requiring the coagulation of soft tissue and for general skin resurfacing procedures.

aimTo help inform clinical decision-making about the dual 1440/1927-nm NFDL system, particularly for treating patients with diverse skin types who require safe and effective resurfacing treatments.

methodsA PubMed search of literature was conducted to review safety and tolerability outcomes from clinical studies of 1440- and 1927-nm NFDL treatments.

resultsExpected skin reactions, including erythema, edema, and crusting, were mild to moderate and self-limited for concurrent and individual use of the 1440- and 1927-nm handpieces. Mild discomfort and heat sensation, which were also expected, indicated that treatment was well tolerated. Safety was also demonstrated in patients with skin of color, with no serious AEs. Levels of patient satisfaction were high.

conclusionsThe dual 1440/1927-nm NFDL system is a safe and well-tolerated option for resurfacing of diverse skin types with minimal postprocedural downtime and reduced risk of AEs relative to ablative lasers.

Indexed as

Cosmetic TechniquesLasers, SemiconductorSkin AgingErythemaHumansSkinSkin PigmentationTreatment Outcome1440 nm1927 nmdiodefractionallasernon‐ablativesafety

Identifiers

PMID41229184
PMCPMC12612654

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.