ArticleMolecular plant pathology2025
A Cystine Transporter Mediates Nutrient Acquisition and Redox Balance During Wheat Stripe Rust Infection.
Article in Molecular plant pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- The Characterization and Antifungal Efficacy of NJ-62 Protein from Weizmannia coagulans CGMCC 9951 against Ceratocystis fimbriata.Probiotics and antimicrobial proteins · 2026Article
- Article
- A Cystine Transporter Mediates Nutrient Acquisition and Redox Balance During Wheat Stripe Rust Infection.Molecular plant pathology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Amino acid uptake is crucial for the pathogenicity of Puccinia striiformis f. sp. tritici (Pst), the causative agent of wheat stripe rust. In this study, we investigated the dynamics of cystine accumulation in wheat leaves during Pst infection and identified Pst cystine transporters involved in this process. Amino acid profiling revealed a marked increase in cystine content at early infection stages. Phylogenetic analysis and expression profiling identified four candidate Pst cystine transporter genes, among which PstAZ2B02G00053 (designated as PstCYN1) was functionally validated through yeast complementation assays. Subcellular localisation studies confirmed PstCYN1 as a plasma membrane transporter. Silencing of PstCYN1 via BSMV-VIGS and RNAi significantly reduced Pst virulence, as evidenced by decreased fungal biomass, reduced haustorial formation and fewer urediniospore pustules. Furthermore, apoplastic cystine accumulation and reactive oxygen species (ROS) levels were elevated in PstCYN1-silenced plants, indicating that PstCYN1 mediates not only cystine uptake but also redox regulation at the infection interface. These findings highlight the critical role of PstCYN1 in Pst nutrient acquisition and defence suppression, providing potential targets for enhancing wheat resistance against stripe rust.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.