Evidence map›Paper›PMID 41229161›Full record

ArticleMedical care research and review : MCRR2026

Do Must-Access Prescription Drug Monitoring Programs (PDMPs) Affect Pain and Impairment Outcomes in Older Adults?

Martha Wetzel, David H Howard, Nicholas A Giordano, Stephen W Patrick, Courtney R Yarbrough

Abstract read
In one paragraph

Article in Medical care research and review : MCRR, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Martha WetzelEmory University, Atlanta, GA, USA.ORCID 0000-0002-7533-3729
David H HowardEmory University, Atlanta, GA, USA.
Nicholas A GiordanoEmory University, Atlanta, GA, USA.
Stephen W PatrickEmory University, Atlanta, GA, USA.
Courtney R YarbroughEmory University, Atlanta, GA, USA.

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Training in Advanced Data Analytics to End Drug-Related Harms (TADA)T32DA050552 · NIDA · EMORY UNIVERSITY · PI Howard H Chang, Hannah LF Cooper · 2020 to 2026
$1.6M
NIA NIH HHS U01 AG009740NIDA NIH HHS T32 DA050552
6 · The paper itself

Abstract

State policies requiring clinicians to review prescription drug monitoring program (PDMP) databases have proliferated. However, patient advocates suggest these policies may adversely affect patients with chronic pain. This study aimed to quantify the effect of must-access PDMP implementation on pain and physical impairment. Using panel data on 34,431 older adults from the Health and Retirement Study (2002-2021), we conducted a heterogeneity-robust difference-in-differences analysis. Must-access PDMPs were associated with a 1.65 (95% CI: 0.43 to 2.87) percentage point increase in frequent pain during the two-year window surrounding policy implementation and a peak 3.52 (95% CI: 0.88 to 6.16) percentage point increase in the second post-policy period, after which the effect dissipated. Effects on impairment outcomes were positive but statistically insignificant. Findings suggest that must-access PDMP policies may increase numbers of older adults reporting frequent pain in the early policy implementation years, though they were not associated with statistically detectable changes in physical impairment.

Indexed as

Chronic PainPrescription Drug Monitoring ProgramsAgedAged, 80 and overFemaleHumansMaleUnited Statesolder adultsopioidspainprescription drug monitoring programs

Identifiers

PMID41229161
PMCPMC12751355

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.