Evidence map›Paper›PMID 41229081›Full record

SynthesisJournal of cutaneous medicine and surgery

Surgical Interventions in Advanced Hidradenitis Suppurativa: A Systematic Review.

Michal Moshkovich, Edgar Akuffo-Addo, Emily Volfson, Jonah Perlmutter, Rebecca Yakubov, Romy Levy, Amrit Thandi, Ammar Saed Aldien, Katya Peri, Ilya Mukovozov

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of cutaneous medicine and surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Michal MoshkovichTemerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID 0009-0001-7612-3950
Edgar Akuffo-AddoDivision of Dermatology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-8867-0935
Emily VolfsonTemerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID 0009-0006-1120-2734
Jonah PerlmutterTemerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0001-5230-7168
Rebecca YakubovFaculty of Medicine, University of Ottawa, Ottawa, Canada.
Romy LevyTemerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Amrit ThandiTemerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID 0009-0005-9301-9230
Ammar Saed AldienFaculty of Medicine and Health Sciences, McGill University, Montréal, Québec, Canada.ORCID 0000-0003-4945-8293
Katya PeriFaculty of Medicine and Health Sciences, McGill University, Montréal, Québec, Canada.ORCID 0000-0002-7367-7501
Ilya MukovozovDivision of Dermatology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0003-1058-9413

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHidradenitis suppurativa (HS) is a chronic, immune-mediated skin disorder affecting intertriginous areas, frequently leading to painful nodules, abscesses, sinus tracts, and scarring. In patients with moderate-to-severe disease (Hurley Stages II and III), surgical intervention is frequently required to achieve durable disease control.

objectiveTo compare and evaluate the surgical interventions employed in Hurley Stage II and III HS by evaluating recurrence rates, postoperative complications, and patient-centred outcomes across different operative modalities.

methodsA comprehensive search of MEDLINE and EMBASE identified studies reporting surgical outcomes in Hurley Stage II and III HS. English-language studies describing postoperative recurrence, complications, and patient-centred outcomes stratified by surgical intervention were included. Of 647 studies screened, 136 studies were included.

resultsA total of 136 studies were included (5,646 procedures). Primary closure had the highest recurrence (38.0%) and complication rates (29.4%). Wide excision (n = 1923) showed moderate recurrence (17.2%) and the highest cosmetic dissatisfaction. Laser-assisted surgery had the lowest complication rate (2.2%) and recurrence rate (5.7%). Flaps and grafts showed higher complication rates but fewer recurrences than primary closure.

conclusionSurgical outcomes in advanced HS vary by intervention. Primary closure is associated with the highest rates of recurrence and complications, while wide excision and laser-assisted surgery may offer improved disease control. These findings support individualized surgical planning in Stage II and III HS.

Indexed as

Hidradenitis SuppurativaHumansLaser TherapyPostoperative ComplicationsRecurrenceSeverity of Illness IndexSkin TransplantationSurgical FlapsflapgraftHidradenitis suppurativalaserwide excision

Identifiers

PMID41229081
PMCPMC13216569

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.