Evidence map›Paper›PMID 41228828›Full record

ArticleSensors (Basel, Switzerland)2025

The Effect of Knee Extension Limitation on Lumbar Intervertebral Disc Compression Force During Walking: A 3D Musculoskeletal Analysis.

Yuhei Kotaki, Daisuke Kudo, Ryota Kimura, Yuji Kasukawa, Hiroaki Kijima, Hidetomo Saito, Michio Hongo, Takehiro Iwami, Naohisa Miyakoshi

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuhei KotakiDepartment of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan.
Daisuke KudoDepartment of Rehabilitation Medicine, Akita University Hospital, 1-1-1 Hondo, Akita 010-8543, Japan.ORCID 0000-0001-8626-1057
Ryota KimuraDepartment of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan.ORCID 0000-0002-4855-3283
Yuji KasukawaDepartment of Rehabilitation Medicine, Akita University Hospital, 1-1-1 Hondo, Akita 010-8543, Japan.ORCID 0000-0001-7008-675X
Hiroaki KijimaDepartment of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan.
Hidetomo SaitoDepartment of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan.
Michio HongoDepartment of Physical Therapy, Akita University Graduate School of Health Sciences, 1-1-1 Hondo, Akita 010-8543, Japan.
Takehiro IwamiDepartment of Systems Design Engineering, Faculty of Engineering Science, Akita University Graduate School of Engineering Science, 1-1 Tegata Gakuen-cho, Akita 010-8502, Japan.
Naohisa MiyakoshiDepartment of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan.ORCID 0000-0001-5175-3350

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Knee-spine interactions suggest that limited knee extension may elevate spinal loading during ambulation in older adults. This study aimed to estimate lumbar intervertebral disc loads during walking in patients with knee extension limitations using a 3D musculoskeletal model and examine their relationship with sagittal alignment. Seventeen adults with radiographic knee osteoarthritis (Kellgren-Lawrence ≥ 2) underwent whole-spine lateral radiography and 3D gait analysis with force plates. A patient-scaled AnyBody model was used to compute intervertebral disc compression forces (T12/L1-L5/S1). Participants were categorized into two groups based on knee extension angle (KEA): a limitation cohort (deficit ≥ 10°) and a non-limitation cohort (<10°). Peak compression force (PCF) and mean compression force were normalized to body weight. The limitation group showed a smaller pelvic incidence and a larger sagittal vertical axis. PCF was significantly increased at the thoracolumbar and upper lumbar levels (T12/L1, L1/2, L2/3, and L3/4), whereas the mean forces remained unchanged. Knee extension limitation is associated with higher peak upper lumbar disc loading during gait, supporting the targeted management of knee extension in older adults at risk of spinal degeneration.

Indexed as

Intervertebral DiscKnee JointLumbar VertebraeWalkingAgedBiomechanical PhenomenaFemaleGaitHumansImaging, Three-DimensionalMaleMiddle AgedOsteoarthritis, KneeWeight-BearingAnyBodygaitknee–spine syndromelumbar spinemusculoskeletal modelingolder adultspeak compression forcesagittal alignment

Identifiers

PMID41228828
PMCPMC12610010

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.