A Novel Demographic Indicator Fusion Network (DIFNet) for Dynamic Fusion of EEG and Demographic Indicators for Robust Depression Detection.

Electroencephalography (EEG) has proven to be effective for detecting major depressive disorder (MDD), with deep learning models further advancing its potential. However, the performance of these models may be limited by their neglect of demographic factors (e.g., age, sex, and education), which are known to influence EEG characteristics of depression. To address this, we propose DIFNet, a deep learning framework that dynamically fuses EEG features with demographic indicators (age, sex, and years of education) to enhance depression recognition accuracy. DIFNet is composed of four modules: a multiscale convolutional module, a Transformer encoder module, a temporal convolutional network (TCN) module, and a demographic indicator fusion module. The fusion model leverages convolution to process demographic vectors and integrates them with spatiotemporal EEG features, thereby embedding demographic indicators within the deep learning model for classification. Cross-validation between data trials showed that the DIFNet fusing age and years of education achieves a superior accuracy of 99.66%; the dynamic fusion mechanism improves accuracy by 0.72% compared to the baseline without fusing demographic indicators (98.94%), outperforming state-of-the-art methods (SparNet 94.37% and DBGCN 98.30%).