Evidence map›Paper›PMID 41228606›Full record

ArticlePolymers2025

Poly(ethylene glycol)-

Miyu Hashimoto, Kazune Oda, Ari Yamamoto, Ik Sung Cho, Yasuhiko Tabata, Masaya Yamamoto, Tooru Ooya

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Miyu HashimotoDepartment of Medical Device Engineering, Graduate School of Medicine, Kobe University, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 657-0017, Japan.
Kazune OdaDepartment of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, 1-1 Rokkoudai-cho, Nada-ku, Kobe 657-8501, Japan.
Ari YamamotoDepartment of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, 1-1 Rokkoudai-cho, Nada-ku, Kobe 657-8501, Japan.
Ik Sung ChoInstitute for Materials Chemistry and Engineering, Kyushu University, CE41 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.
Yasuhiko TabataLaboratory of Biomaterials, Department of Regeneration Science and Engineering, Institute for Life and Medical Sciences, Kyoto University, South Research Bldg. No. 1, 53 Kawara-cho Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.
Masaya YamamotoDepartment of Materials Processing, Graduate School of Engineering, Tohoku University, 6-6-02 Aramaki-aza Aoba, Aoba-ku, Sendai 980-8579, Japan.
Tooru OoyaDepartment of Medical Device Engineering, Graduate School of Medicine, Kobe University, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 657-0017, Japan.ORCID 0000-0001-7766-5455

Funding

Japan Society for the Promotion of Science JP24K03282
6 · The paper itself

Abstract

Hyaluronic acid (HA) hydrogels are promising biomaterials for tissue engineering and drug delivery due to their biocompatibility and biodegradability. The objective of this study was to develop a novel HA-based hydrogel for the controlled release of basic fibroblast growth factor (bFGF) to promote angiogenesis. A series of PEG-grafted HA hydrogels with varying PEG grafting ratios were synthesized and characterized. We evaluated their physicochemical properties, including swelling ratio, cross-linking density, and enzymatic degradation behavior, and assessed their ability to control bFGF release and induce angiogenesis in a mouse model. The results showed that the PEG-grafting ratio significantly affected the gel properties. Notably, the PEG60-

Indexed as

angiogenesisgrowth factorhyaluronic acidhydrogelsPoly(ethylene glycol)

Identifiers

PMID41228606
PMCPMC12608165

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.