Evidence map›Paper›PMID 41228599›Full record

ArticlePolymers2025

Nanomedicines for Delivery of Cytarabine: Effect of Carrier Structure and Spacer on the Anti-Lymphoma Efficacy.

Robert Pola, Eliška Grosmanová, Michal Pechar, Libor Kostka, Eva Pokorná, Liliana Tušková, Pavel Klener, Tomáš Etrych

Abstract read
In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Robert PolaInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, 162 00 Prague, Czech Republic.ORCID 0000-0003-0025-2016
Eliška GrosmanováInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, 162 00 Prague, Czech Republic.ORCID 0000-0003-3877-002X
Michal PecharInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, 162 00 Prague, Czech Republic.ORCID 0000-0002-4507-1801
Libor KostkaInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, 162 00 Prague, Czech Republic.ORCID 0000-0002-7770-1855
Eva PokornáInstitute of Pathological Physiology, First Faculty of Medicine, Charles University, Prague, U Nemocnice 5, 128 53 Prague, Czech Republic.
Liliana TuškováInstitute of Pathological Physiology, First Faculty of Medicine, Charles University, Prague, U Nemocnice 5, 128 53 Prague, Czech Republic.
Pavel KlenerInstitute of Pathological Physiology, First Faculty of Medicine, Charles University, Prague, U Nemocnice 5, 128 53 Prague, Czech Republic.
Tomáš EtrychInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, 162 00 Prague, Czech Republic.ORCID 0000-0001-5908-5182

Funding

Ministry of Health of the Czech Republic NU22-08-00148National Institute for Cancer Research LX22NPO5102
6 · The paper itself

Abstract

High-dose therapy with cytarabine (araC) is a standard treatment for aggressive non-Hodgkin lymphomas, but its efficacy is limited by rapid enzymatic degradation. To overcome this, araC was conjugated to

Indexed as

cytarabinedrug deliveryHPMA copolymermantle cell lymphomananotherapeutics

Identifiers

PMID41228599
PMCPMC12610423

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.