Evidence map›Paper›PMID 41228459›Full record

ArticleNutrients2025

Natural Compound Melatonin Suppresses Breast Cancer Development by Regulating Circadian Rhythm.

Yuanli He, Chenchen Hu, Feiming Hu, Yuanjie Sun, Lin Guo, Junyi Ren, Chenying Han, Yuhui Li, Xiyang Zhang, Yubo Sun and 6 more

Abstract read
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yuanli HeDepartment of Immunology, Air Force Medical University, No. 169, Changle West Road, Xi'an 710032, China.
Chenchen HuDepartment of Immunology, Air Force Medical University, No. 169, Changle West Road, Xi'an 710032, China.
Feiming HuDepartment of Immunology, Air Force Medical University, No. 169, Changle West Road, Xi'an 710032, China.
Yuanjie SunDepartment of Immunology, Air Force Medical University, No. 169, Changle West Road, Xi'an 710032, China.
Lin GuoDepartment of Immunology, Air Force Medical University, No. 169, Changle West Road, Xi'an 710032, China.
Junyi RenSchool of Basic Medicine, Air Force Medical University, No. 169, Changle West Road, Xi'an 710032, China.
Chenying HanDepartment of Immunology, Air Force Medical University, No. 169, Changle West Road, Xi'an 710032, China.
Yuhui LiSchool of Basic Medicine, Air Force Medical University, No. 169, Changle West Road, Xi'an 710032, China.
Xiyang ZhangMilitary Medical Innovation Center, Air Force Medical University, Xi'an 710032, China.
Yubo SunDepartment of Immunology, Air Force Medical University, No. 169, Changle West Road, Xi'an 710032, China.
Junqi ZhangDepartment of Immunology, Air Force Medical University, No. 169, Changle West Road, Xi'an 710032, China.
Sirui CaiDepartment of Immunology, Air Force Medical University, No. 169, Changle West Road, Xi'an 710032, China.
Yueyue WangDepartment of Immunology, Air Force Medical University, No. 169, Changle West Road, Xi'an 710032, China.
Dongbo JiangDepartment of Immunology, Air Force Medical University, No. 169, Changle West Road, Xi'an 710032, China.ORCID 0000-0002-2675-5634
Kun YangDepartment of Immunology, Air Force Medical University, No. 169, Changle West Road, Xi'an 710032, China.
Shuya YangDepartment of Immunology, Air Force Medical University, No. 169, Changle West Road, Xi'an 710032, China.ORCID 0000-0001-8884-7254

Funding

Key Laboratory Projects of the Shaanxi Provincial Natural Science Basic Research Program 2025SYS-SYSZD-028National Natural Science Foundation of China 82372822National Natural Science Foundation of China 82573107The Young Talent Fund of Association for Science and Technology in Shaanxi, China 20240324
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Breast NeoplasmsCircadian RhythmMelatoninAnimalsApoptosisARNTL Transcription FactorsCell Line, TumorCell ProliferationFemaleGene Expression Regulation, NeoplasticGlucoseHumansMCF-7 CellsMiceARNTL Transcription FactorsBMAL1 protein, humanGlucoseMelatoninALDH3A1BMAL1breast cancercircadian rhythmglycolysismelatonin

Identifiers

PMID41228459
PMCPMC12609774

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.