Evidence map›Paper›PMID 41228402›Full record

ArticleNutrients2025

Single-Cell RNA-Seq Identifies Immune Remodeling in Lungs of β-Carotene Oxygenase 2 Knockout Mice with Improved Antiviral Response.

Yashu Tang, William Lin, Xiang Chi, Huimin Chen, Dingbo Lin, Winyoo Chowanadisai, Xufang Deng, Peiran Lu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yashu TangDepartment of Nutritional Sciences, Oklahoma State University, Stillwater, OK 74078, USA.
William LinDepartment of Nutritional Sciences, Oklahoma State University, Stillwater, OK 74078, USA.
Xiang ChiDepartment of Physiological Sciences, Oklahoma State University, Stillwater, OK 74078, USA.ORCID 0009-0003-4853-7931
Huimin ChenDepartment of Nutritional Sciences, Oklahoma State University, Stillwater, OK 74078, USA.
Dingbo LinDepartment of Nutritional Sciences, Oklahoma State University, Stillwater, OK 74078, USA.ORCID 0000-0002-7441-8210
Winyoo ChowanadisaiDepartment of Nutritional Sciences, Oklahoma State University, Stillwater, OK 74078, USA.
Xufang DengDepartment of Physiological Sciences, Oklahoma State University, Stillwater, OK 74078, USA.ORCID 0000-0002-7604-3627
Peiran LuCenter for Mitochondrial and Epigenetic Medicine and Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.ORCID 0009-0001-5096-3046

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

beta-Carotene 15,15'-MonooxygenaseCOVID-19DioxygenasesLungAnimalsImmunity, InnateMiceMice, Inbred C57BLMice, KnockoutRNA-SeqSARS-CoV-2Single-Cell AnalysisSingle-Cell Gene Expression AnalysisBco2 protein, mousebeta-Carotene 15,15'-MonooxygenaseDioxygenasesdendritic cellsinterferon signalinglung immune heterogeneitySARS-CoV2 viral infectionsingle-cell RNA sequencing (scRNA-seq)T cells

Identifiers

PMID41228402
PMCPMC12610359

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.