Evidence map›Paper›PMID 41228334›Full record

ArticleCancers2025

Neutrophil Dynamics Contribute to Disease Progression and Poor Survival in Pancreatic Cancer.

Reegan Sturgeon, Paran Goel, Caitlin Molczyk, Ridhi Bhola, Paul M Grandgenett, Michael A Hollingsworth, Rakesh K Singh

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Reegan SturgeonDepartment of Pathology, Microbiology, and Immunology, The University of Nebraska Medical Center, Omaha, NE 68198, USA.ORCID 0009-0002-6743-9723
Paran GoelDivision of Hematology and Oncology, The University of Alabama, Birmingham, AL 35294, USA.ORCID 0009-0000-6494-632X
Caitlin MolczykDepartment of Pathology, Microbiology, and Immunology, The University of Nebraska Medical Center, Omaha, NE 68198, USA.
Ridhi BholaDepartment of Pathology, Microbiology, and Immunology, The University of Nebraska Medical Center, Omaha, NE 68198, USA.
Paul M GrandgenettEppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Michael A HollingsworthEppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Rakesh K SinghDepartment of Pathology, Microbiology, and Immunology, The University of Nebraska Medical Center, Omaha, NE 68198, USA.ORCID 0000-0002-1317-3520

Funding

UNMC/EPPLEY CANCER CENTER SUPPORT GRANTP30CA036727 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI James Eudy · 1985 to 2026
$55.0M
Pancreatic Cancer Detection ConsortiumU01CA210240 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Michael A. Hollingsworth · 2017 to 2026
$12.9M
CHEMICAL CARCINOGENESIS &CANCER BIOLOGYT32CA009476 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Jennifer D. Black · 1988 to 2026
$6.2M
Targeting CXCR2 axis in Pancreatic CancerR01CA228524 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BATRA, SURINDER K., SINGH, RAKESH K · 2018 to 2022
$2.0M
Critical Resources Provided by UNMC Rapid Autopsy Program (RAP) Biorepository Stimulate Cancer ResearchR50CA211462 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Paul M Grandgenett · 2016 to 2026
$1.4M
National Cancer Center R01CA228524NCI NIH HHS P30 CA036727NCI NIH HHS R01 CA228524NCI NIH HHS R50 CA211462NCI NIH HHS T32 CA009476NCI NIH HHS U01 CA210240
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cancer immunologyCXCR2pancreatic cancertumor-associated neutrophilstumor microenvironment

Identifiers

PMID41228334
PMCPMC12607450

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.