Evidence map›Paper›PMID 41228311›Full record

ArticleCancers2025

Daily Consumption of Apigenin Prevents Acute Lymphoma/Lymphoblastic Leukemia in Male C57BL/6J Mice Exposed to Space-like Radiation.

Tanat Peanlikhit, Jingxuan Liu, Tahmeena Ahmed, James S Welsh, Tobias Karakach, Kenneth R Shroyer, Elbert Whorton, Kanokporn Noy Rithidech

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Research Progress on Dietary Intervention in Radiation Protection.Dose-response : a publication of International Hormesis Society
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tanat PeanlikhitDepartment of Pathology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794, USA.
Jingxuan LiuDepartment of Pathology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794, USA.
Tahmeena AhmedDepartment of Pathology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794, USA.
James S WelshDepartment of Radiation Oncology, Loyola University Health System, Maywood, IL 60153, USA.
Tobias KarakachDepartment of Pharmacology, Dalhousie University, Halifax, NS B3H 4R2, Canada.ORCID 0000-0003-2460-3781
Kenneth R ShroyerDepartment of Pathology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794, USA.
Elbert WhortonStatCom, P.O. Box 3041, Galveston, TX 77551, USA.
Kanokporn Noy RithidechDepartment of Pathology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794, USA.ORCID 0000-0002-7153-091X

Funding

NASA # 80NSSC19K0435
6 · The paper itself

Abstract

introductionThe work presented here is part of our study series aimed at investigating the countermeasure effectiveness of apigenin (AP) against both early and late effects of heavy silicon (

methodMice received a diet containing 20 mg/kg body weight of AP for five days before and after total-body irradiation with either 0 or 0.5 Gy of 260 MeV

resultsAt 770 days, survival rates were 37% for

conclusionOur findings demonstrate that AP is an effective means of tackling the challenges posed by space radiation, and it has the potential to revolutionize protection in this critical area.

Indexed as

apigeninchemopreventionlymphoblastic leukemiamitigationprotectionspace radiation

Identifiers

PMID41228311
PMCPMC12607309

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.