Evidence map›Paper›PMID 41228263›Full record

ReviewCancers2025

Desmoid Tumors-Experience from a Referral Center, Part 1: Multidisciplinary Review and Practical Recommendations.

Alvarez Alvarez Rosa, Agra Pujol Carolina, Arregui Valles Marta, Alijo Francisco, Fernández Gonzalo Adriana, Gutiérrez Natalia, Lozano Lominchar Pablo, Mata Fernández Cristina, Mediavilla Santos Lidia, Novo Ulrike and 4 more

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Alvarez Alvarez RosaMedical Oncology Department, Instituto de Investigacion Sanitaria Gregorio Marañon, Hospital General Universitario Gregorio Marañon, 28007 Madrid, Spain.ORCID 0000-0003-0935-8298
Agra Pujol CarolinaDepartment of Pathology, Hospital Gregorio Marañon, Complutense University, 28007 Madrid, Spain.
Arregui Valles MartaMedical Oncology Department, Instituto de Investigacion Sanitaria Gregorio Marañon, Hospital General Universitario Gregorio Marañon, 28007 Madrid, Spain.
Alijo FranciscoRadiology Department, Hospital General Universitario Gregorio Marañon, 28007 Madrid, Spain.ORCID 0000-0002-8851-3948
Fernández Gonzalo AdrianaRadiology Department, Hospital General Universitario Gregorio Marañon, 28007 Madrid, Spain.
Gutiérrez NataliaMedical Oncology Department, Instituto de Investigacion Sanitaria Gregorio Marañon, Hospital General Universitario Gregorio Marañon, 28007 Madrid, Spain.
Lozano Lominchar PabloGeneral Surgery and Surgical Oncology Department, Hospital Universitario Gregorio Marañon, Complutense University, 28007 Madrid, Spain.ORCID 0000-0002-5413-8449
Mata Fernández CristinaPediatric and Adolescent Oncohematology Unit, Pediatric Sarcomas National Reference Center, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.ORCID 0000-0001-9922-0078
Mediavilla Santos LidiaOrthopedic Surgery and Traumatology Department, Musculoskeletal Oncology Section, Hospital Universitario Gregorio Marañon, 28007 Madrid, Spain.
Novo UlrikeRadiology Department, Hospital General Universitario Gregorio Marañon, 28007 Madrid, Spain.ORCID 0000-0002-2172-8960
Santos MarinaRadiation Oncology Department, Hospital Universitario Gregorio Marañon, 28007 Madrid, Spain.ORCID 0009-0005-0175-6509
Hernández Torrado GuillermoMedical Oncology Department, Instituto de Investigacion Sanitaria Gregorio Marañon, Hospital General Universitario Gregorio Marañon, 28007 Madrid, Spain.
Carpintero García HenarOrthopedic Surgery and Traumatology Department, Musculoskeletal Oncology Section, Hospital Universitario Gregorio Marañon, 28007 Madrid, Spain.
Gutiérrez-Ortiz de la Tabla AnaMedical Oncology Department, Hospital Universitario Infanta Leonor, 28031 Madrid, Spain.ORCID 0000-0002-6080-0195

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Desmoid tumors (DTs), also known as aggressive fibromatosis, are rare neoplasms characterized by local invasiveness and a high risk of recurrence, despite their lack of metastatic potential. The management of these tumors remains challenging due to their unpredictable behavior and heterogeneous presentations. In this two-part study, we first provide a comprehensive review of the scientific evidence on diagnosis and emerging therapeutic strategies for DT. In the second part, we will present a retrospective analysis of our experience at a national reference center for sarcoma treatment, focusing on diagnostic strategies, therapeutic interventions, and clinical outcomes.

Indexed as

active surveillanceCTNNB1 mutationdesmoid tumordesmoid-type fibromatosisextra-abdominal desmoidsfamilial adenomatous polyposisintra-abdominal desmoidsmultidisciplinary managementreferral center experience

Identifiers

PMID41228263
PMCPMC12609056

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.