Evidence map›Paper›PMID 41227699›Full record

ArticleFoods (Basel, Switzerland)2025

Risk Assessment of Dietary Exposure to Fluoride from Follow-On Milk Consumption.

Santiago Cerdán-Pérez, Soraya Paz-Montelongo, Samuel Alejandro-Vega, Carmen Rubio, Ángel J Gutiérrez, Arturo Hardisson, Chaxiraxi de la Cruz Morales, Inés A Revelo-Mejía, Javier Darias-Rosales, Natalia Pérez-Rodríguez and 1 more

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Santiago Cerdán-PérezArea of Toxicology, Universidad de La Laguna, 38071 La Laguna, Tenerife, Spain.
Soraya Paz-MontelongoArea of Toxicology, Universidad de La Laguna, 38071 La Laguna, Tenerife, Spain.
Samuel Alejandro-VegaArea of Toxicology, Universidad de La Laguna, 38071 La Laguna, Tenerife, Spain.ORCID 0000-0003-0775-5732
Carmen RubioArea of Toxicology, Universidad de La Laguna, 38071 La Laguna, Tenerife, Spain.ORCID 0000-0001-8774-5870
Ángel J GutiérrezArea of Toxicology, Universidad de La Laguna, 38071 La Laguna, Tenerife, Spain.ORCID 0000-0003-1581-0850
Arturo HardissonArea of Toxicology, Universidad de La Laguna, 38071 La Laguna, Tenerife, Spain.
Chaxiraxi de la Cruz MoralesArea of Pharmacology, Universidad de La Laguna, 38071 La Laguna, Tenerife, Spain.ORCID 0000-0001-6947-8238
Inés A Revelo-MejíaFacultad de Odontología, Universidad Antonio Nariño, Bogotá 110231, Colombia.
Javier Darias-RosalesArea of Toxicology, Universidad de La Laguna, 38071 La Laguna, Tenerife, Spain.
Natalia Pérez-RodríguezOncologia Médica, Hospital Universitario Nuestra Señora de Candelaria, 38010 Santa Cruz de Tenerife, Tenerife, Spain.ORCID 0009-0007-4693-9178
Consuelo RevertDepartamento de Medicina Física y Farmacología, Universidad de La Laguna, 38071 La Laguna, Tenerife, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breastfeeding based on the use of follow-on milk may contain traces of xenobiotic elements that could pose a risk to the health of the vulnerable population for which it is intended. Fluorine is a non-essential element that, at high concentrations, can produce adverse health effects such as dental fluorosis, decreased IQ (intelligence quotient), thyroid alterations, and kidney damage. Given the vulnerability of infants and the possible presence of fluoride in this type of product, the content of this anion was determined in a total of 46 samples of follow-on milk from different brands and types (starter, follow-on, and hydrolysate formulas) using a fluoride ion-selective electrode (EWI). The highest mean concentration of fluoride was recorded in the hydrolysate formulas (3.38 ± 2.78 mg/L). The dietary intake assessment indicated that some brands of hydrolyzed formulas could pose a health risk, providing up to 94.1% of the UL (upper level) with only one 90 mL serving in the 0-6-month age group. It is recommended that consumers be aware of the fluoride content in the water used to prepare bottles, as it can further increase total fluoride intake and therefore pose a risk to the health of infants.

Indexed as

exposure assessmentfluoridefluorosisfollow-on milktoxicity

Identifiers

PMID41227699
PMCPMC12609763

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.