Evidence map›Paper›PMID 41227614›Full record

ReviewFoods (Basel, Switzerland)2025

Recent Advances Towards Selenium Nanoparticles: Synthetic Methods, Functional Mechanisms, and Biological Applications.

Lulu Geng, Linling Li, Xuening Sun, Shuiyuan Cheng, Jiangling He

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lulu GengNational R&D Center for Se-rich Agricultural Products Processing, Wuhan Polytechnic University, Wuhan 430023, China.
Linling LiSchool of Modern Industry for Selenium Science and Engineering, Wuhan Polytechnic University, Wuhan 430023, China.
Xuening SunNational R&D Center for Se-rich Agricultural Products Processing, Wuhan Polytechnic University, Wuhan 430023, China.
Shuiyuan ChengNational R&D Center for Se-rich Agricultural Products Processing, Wuhan Polytechnic University, Wuhan 430023, China.
Jiangling HeNational R&D Center for Se-rich Agricultural Products Processing, Wuhan Polytechnic University, Wuhan 430023, China.ORCID 0000-0003-1511-6260

Funding

The National Natural Science Foundation of China No. 62505237The Research and Innovation Initiatives of WHPU No. 2025Y29The Research Funding of Wuhan Polytechnic University No. 2022RZ070The Science and Technology Research Project of Hubei Provincial Department of Education No. B2024063Wuhan Talents - Outstanding Young Talents Project Funding of Jiangling He No.
6 · The paper itself

Abstract

The exceptional physicochemical properties of selenium nanoparticles (SeNPs) have led to their widespread development. The function of SeNPs is significantly influenced by their shape and particle size, which are in turn determined by the applied synthesis methods. This work presents a critical and comparative analysis of physical, chemical, and biosynthetic methods. The key point is to elaborate on how different methods precisely regulate the particle size, morphology, and stability that are crucial to their functional efficacy. This work emphasizes the importance of creating standardized protocols for characterizing SeNPs in order to make meaningful comparisons between the effectiveness of various studies. We further elucidate the underlying mechanisms of SeNPs' anti-tumor, antioxidant, and antibacterial activities. A key novelty of this work lies in its systematic construction of a bridge between the synthesis, properties, functions, applications, and translational potential and its provision of a critical assessment. Finally, the review identifies and summarizes the principal challenges hindering clinical and commercial translation, including the imperative for standardized toxicological evaluation, scalable synthesis, and regulatory alignment.

Indexed as

biological applicationfunctional mechanismselenium nanoparticlesynthetic method

Identifiers

PMID41227614
PMCPMC12607590

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.