Evidence map›Paper›PMID 41227613›Full record

ReviewFoods (Basel, Switzerland)2025

From Waste to Wealth: Unlocking the Potential of Cellulase Characteristics for Food Processing Waste Management.

Muhammad Hammad Hussain, Kamran Ashraf, Redhwan Ebrahim Abdullah Alqudaimi, Maria Martuscelli, Shao-Yuan Leu, Salim-Ur Rehman, Muhammad Shahbaz Aslam, Zhanao Li, Adnan Khaliq, Yingping Zhuang and 2 more

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Muhammad Hammad HussainState Key Laboratory of Bioreactor Engineering East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.
Kamran AshrafState Key Laboratory of Bioreactor Engineering East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.
Redhwan Ebrahim Abdullah AlqudaimiState Key Laboratory of Bioreactor Engineering East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.
Maria MartuscelliDepartment of Bioscience and Food, Agricultural and Environmental Technology, University of the Studies of Teramo, Via Balzarini 1, 64100 Teramo, Italy.ORCID 0000-0002-5919-305X
Shao-Yuan LeuDepartment of Civil and Environmental Engineering, The Hong Kong Polytechnic University, Hong Kong, China.ORCID 0000-0001-7262-1453
Salim-Ur RehmanDepartment of Food Science and Technology, Riphah International University Faisalabad Campus, Faisalabad 38000, Pakistan.
Muhammad Shahbaz AslamSchool of Biochemistry and Biotechnology, University of the Punjab, Quaid-e-Azam Campus, Lahore 54590, Pakistan.ORCID 0000-0003-4114-5487
Zhanao LiState Key Laboratory of Bioreactor Engineering East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.ORCID 0009-0004-2749-284X
Adnan KhaliqInstitute of Food Science and Technology, Khwaja Fareed University of Engineering and Information Technology, Rahim Yar Khan 64200, Pakistan.
Yingping ZhuangState Key Laboratory of Bioreactor Engineering East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.ORCID 0000-0002-6772-7306
Meijin GuoState Key Laboratory of Bioreactor Engineering East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.
Ali MohsinState Key Laboratory of Bioreactor Engineering East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.ORCID 0000-0001-6564-9810

Funding

National Natural Science Foundation of China 22250410275
6 · The paper itself

Abstract

A surge in environmental pollution compels society to utilize food processing wastes to produce valuable compounds. Enzymatic technology, specifically cellulase-mediated hydrolysis, provides an eco-friendly and effective approach for treating food processing leftovers. The main objective of this review is to explore the significant contributions of cellulase, both in industrial settings and from an environmental perspective. Therefore, this review covers all the aspects of cellulase structural identification, classification, and evolution to its profound applications. The review initially explores cellulases' structural and functional characteristics based on the catalytic and cellulose-binding domains and discusses cellulases' evolutionary origin. A thorough understanding of cellulase properties is essential for overcoming the challenges associated with its commercial production for various applications. In this regard, the optimization for cellulase production through several approaches, including rational design, direct evolution, genetic engineering, and fermentation technology, is also reviewed. In addition, it also underscores the significance of agro-industrial biorefineries, which provide scalable and sustainable solutions to meet future demands for food, chemicals, materials, and fuels. Finally, the last sections of the review solely highlight the potential applications of microbial cellulases in bioremediation. In summary, this review outlines the role of cellulase in efficient valorization aimed at producing multiple bioproducts and the enhancement of environmental remediation efforts.

Indexed as

agroindustrial-based biorefineriesbioremediationcellulasefermentation technologyfood processing wastesgenetic engineering

Identifiers

PMID41227613
PMCPMC12609622

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.