Sequential Galacto- and Xylo-Oligosaccharide Feeding Transiently Modulates Gut Microbiota and Upregulates Intestinal Alkaline Phosphatase in Weaning Piglets.

James S Stanley, Stephen C Mansbridge, Michael R Bedford, Ian F Connerton, Kenneth H Mellits

Abstract read

In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

James S StanleyDivision of Microbiology, Brewing, and Biotechnology, School of Biosciences, University of Nottingham, Loughborough LE12 5RD, UK.ORCID 0000-0003-2972-5358

Stephen C MansbridgeAnimal Science Research Centre, Harper Adams University, Newport TF10 8NB, UK.ORCID 0000-0003-4246-9782

Michael R BedfordSBNS Ltd., Wiltshire SN8 1QJ, UK.ORCID 0000-0002-5308-4290

Ian F ConnertonDivision of Microbiology, Brewing, and Biotechnology, School of Biosciences, University of Nottingham, Loughborough LE12 5RD, UK.ORCID 0000-0001-8652-8938

Kenneth H MellitsDivision of Microbiology, Brewing, and Biotechnology, School of Biosciences, University of Nottingham, Loughborough LE12 5RD, UK.

Funding

Biotechnology and Biological Sciences Research Council BB/T008369/1

6 · The paper itself

Abstract

Improving growth and health at weaning remains a priority in pig production. This study investigates whether supplementation with galacto-oligosaccharides (GOSs) followed by xylo-oligosaccharides (XOSs) improves performance and gut health of healthy 28-day old weaning piglets. Pigs received either a control basal (CON) diet, the CON diet containing 1% GOS for 7 days followed by the CON diet containing 0.017% XOS for 47 days (GXOS), or the CON diet for 7 days followed by the CON diet containing 0.017% XOS for 47 days (XOS). Body weight, average daily gain, average daily feed intake, and feed conversion ratio did not differ between diets from day 1 of weaning (d1) to d54. At d7, GXOS pigs showed increased jejunal and caecal α-diversity (Shannon, inverse Simpson), distinct ileal β-diversity (Yu and Clayton, Bray-Curtis, Jaccard), and greater short-chain fatty acid-producing

Indexed as

dietary carbohydratesgrowthhistologyimmunityintestinal healthmicrobiotaoligosaccharidespigsprebiotics

Identifiers

PMID41227540

DOI10.3390/ani15213210

PMCPMC12609449

What OpenQuestion holds

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LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.