Spatial Modularity of Innate Immune Networks Across Bactrian Camel Tissues.

Lili Guo, Bin Liu, Chencheng Chang, Fengying Ma, Le Zhou, Wenguang Zhang

Abstract read

In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lili GuoInner Mongolia Engineering Research Center of Genomic Big Data for Agriculture, Inner Mongolia Agricultural University, Hohhot 010010, China.ORCID 0000-0002-0387-2045

Bin LiuInner Mongolia Bionew Technology Co., Ltd., Hohhot 010010, China.

Chencheng ChangInner Mongolia Engineering Research Center of Genomic Big Data for Agriculture, Inner Mongolia Agricultural University, Hohhot 010010, China.ORCID 0000-0001-7146-2067

Fengying MaInner Mongolia Engineering Research Center of Genomic Big Data for Agriculture, Inner Mongolia Agricultural University, Hohhot 010010, China.

Le ZhouInner Mongolia Engineering Research Center of Genomic Big Data for Agriculture, Inner Mongolia Agricultural University, Hohhot 010010, China.

Wenguang ZhangInner Mongolia Engineering Research Center of Genomic Big Data for Agriculture, Inner Mongolia Agricultural University, Hohhot 010010, China.

Funding

Department of Science and Technology of Inner Mongolia Autonomous Region 2019ZD016

6 · The paper itself

Abstract

The Bactrian camel exemplifies mammalian adaptation to deserts, but the spatial organization of its innate immune system remains uncharacterized. This study integrated transcriptomes from 110 samples across 11 major tissues and organs to resolve tissue-specific gene expression and innate immune modularity. Through differential expression analysis, Tau specificity index (τ > 0.8), and machine learning validation (Random Forest F1-score = 0.86 ± 0.11), we identified 4242 high-confidence tissue-specific genes (e.g.,

Indexed as

Bactrian camelgene co-expression networkinnate immune generandom forestRNA-seq

Identifiers

PMID41227503

DOI10.3390/ani15213173

PMCPMC12607672

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.