Evidence map›Paper›PMID 41227465›Full record

ArticleAnimals : an open access journal from MDPI2025

Integrative Transcriptomic and Proteomic Profiling Identifies PMEL as a Critical Regulator of Melanogenesis in Rex Rabbits.

Shuaishuai Hu, Jingwen Zhang, Pei Zhang, Mingyan Shi, Ying Zhang

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shuaishuai HuLife Science College, Luoyang Normal University, Luoyang 471934, China.ORCID 0009-0009-4796-4863
Jingwen ZhangLife Science College, Luoyang Normal University, Luoyang 471934, China.
Pei ZhangLife Science College, Luoyang Normal University, Luoyang 471934, China.
Mingyan ShiLife Science College, Luoyang Normal University, Luoyang 471934, China.
Ying ZhangLife Science College, Luoyang Normal University, Luoyang 471934, China.

Funding

key scientific research project of higher education institutions in Henan Province 24B180009Natural Science Foundation of Henan 252300421675
6 · The paper itself

Abstract

Coat color is a crucial production trait for fur-bearing animals and significantly influences their economic value. The remarkable diversity of coat colors in rex rabbits not only provides a wide range of market options but also serves as an essential resource for investigating the genetic mechanisms underlying coat color formation. In this study, we conducted integrated transcriptomic and proteomic profiling of skin tissues from black and white Rex Rabbits, revealing the presence of 52 co-expressed genes/proteins. Proteomic analysis revealed a significant upregulation of PMEL (

Indexed as

melaninPMELproteomerex rabbitstranscriptome

Identifiers

PMID41227465
PMCPMC12609467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.