ReviewAnimals : an open access journal from MDPI2025
Effects of Yeast Culture Supplementation on Milk Yield and Milk Composition in Holstein Dairy Cows: A Meta-Analysis.
Review in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Effects of Fibrolytic Enzymes Alone or with Live Yeast on Rumen Microbiota and Fermentation During Grazing-to-Indoor Transition in Dairy Cows.Life (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Yeast culture (YC) is widely used in dairy production to enhance milk yield and quality, yet effects vary due to differences in products, doses, and trial conditions. This meta-analysis evaluated the impact of YC supplementation on milk yield and composition in lactating Holstein cows, aiming to identify effective yeast culture types, dosages, and duration of use. A systematic search of PubMed, Web of Science, and CNKI for randomized controlled trials (RCTs) from 2000 to 2024 was conducted. Following PICOS criteria, 23 RCTs comprising 32 comparisons and over 3200 cows were included. Data were analyzed using RevMan 5.3 and Stata/MP 15.0 to compute standardized mean differences (SMD) and 95% confidence intervals with random-effects models. Subgroup and sensitivity analyses were performed. Results showed that YC supplementation significantly improved milk yield (SMD = 2.14), fat (SMD = 0.57), protein (SMD = 1.34), and lactose content (SMD = 0.61). Subgroup analysis revealed that supplementation with saccharomyces cerevisiae at a dosage of 10-50 g/d effectively increased milk yield during lactation 42-56 d. In contrast, during the lactation 21-30 d, different dosages of saccharomyces cerevisiae exerted differential effects on milk composition: supplementation at 60-120 g/d contributed to an increase in milk fat content, while supplementation at 10-50 g/d significantly enhanced milk protein level. Furthermore, lactose content was not significantly associated with the feeding period of saccharomyces cerevisiae; however, high-dose (>120 g/d) could significantly increase lactose content. Significant heterogeneity (I
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.