Inhalation of Ultrafine Carbon Black-Induced Mitochondrial Dysfunction in Mouse Heart Through Changes in Acetylation.

Rahatul Islam, Jackson E Stewart, William E Mullen, Dena Lin, Salik Hussain, Dharendra Thapa

Abstract read

In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rahatul IslamDivision of Exercise Physiology, Department of Human Performance, School of Medicine, West Virginia University, 1 Medical Center Drive, P.O. Box 9227, Morgantown, WV 26506, USA.ORCID 0000-0002-1889-3316

Jackson E StewartDivision of Exercise Physiology, Department of Human Performance, School of Medicine, West Virginia University, 1 Medical Center Drive, P.O. Box 9227, Morgantown, WV 26506, USA.ORCID 0009-0004-8281-0783

William E MullenDivision of Exercise Physiology, Department of Human Performance, School of Medicine, West Virginia University, 1 Medical Center Drive, P.O. Box 9227, Morgantown, WV 26506, USA.

Dena LinDivision of Exercise Physiology, Department of Human Performance, School of Medicine, West Virginia University, 1 Medical Center Drive, P.O. Box 9227, Morgantown, WV 26506, USA.

Salik HussainDepartment of Physiology, Pharmacology & Toxicology, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.ORCID 0000-0003-0339-6226

Dharendra ThapaDivision of Exercise Physiology, Department of Human Performance, School of Medicine, West Virginia University, 1 Medical Center Drive, P.O. Box 9227, Morgantown, WV 26506, USA.ORCID 0000-0002-1157-5534

Funding

National Heart Lung and Blood Institute HL146905NIEHS NIH HHS ES031253

6 · The paper itself

Abstract

Air pollution, particularly from fine and ultrafine particulate matter (PM), has been increasingly associated with cardiovascular diseases. Ultrafine carbon, a component of ultrafine PM widely used in industrial settings, is both an environmental and occupational hazard. But the cardiac toxicity of repeated inhalation exposure to ultrafine carbon black (CB) remains unclear. In this study, we investigated how repeated inhalation of CB affects cardiac mitochondrial function, focusing on metabolic pathways and regulatory mechanisms involved in energy production. Male C57BL/6J mice were exposed to either filtered air or CB aerosols (10 mg/m

Indexed as

MitochondriaMitochondria, HeartMyocardiumSootAcetylationAnimalsInhalation ExposureLipid PeroxidationMaleMiceMice, Inbred C57BLOxidative StressParticulate MatterSuperoxide DismutaseParticulate MatterSootSuperoxide Dismutasecarbon blacklysine acetylationmetabolismmitochondriareactive oxygen species

Identifiers

PMID41227373

DOI10.3390/cells14211728

PMCPMC12607619

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.