Evidence map›Paper›PMID 41227197›Full record

ArticleJournal of clinical medicine2025

Upadacitinib's Effectiveness and Safety as a Second- or Third-Line Therapy in Patients with Ulcerative Colitis: Data from a Real-World Study.

Giammarco Mocci, Antonio Tursi, Franco Scaldaferri, Daniele Napolitano, Daniela Pugliese, Giovanni Maconi, Giovanni Cataletti, Roberta Pica, Claudio Cassieri, Edoardo Vincenzo Savarino and 54 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

64 authors.

Giammarco MocciDivision of Gastroenterology, AORN "Brotzu" Hospital, 09134 Cagliari, Italy.ORCID 0000-0002-9263-7409
Antonio TursiTerritorial Gastroenterology Service, ASL BAT, 76123 Andria, Italy.ORCID 0000-0001-5767-5541
Franco ScaldaferriDepartment of Medical and Surgical Sciences, School of Medicine, Catholic University, 00168 Rome, Italy.ORCID 0000-0001-8334-7541
Daniele NapolitanoDigestive Diseases Centre (CEMAD), Department of Medical and Surgical Sciences, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Policlinico Universitario "A. Gemelli" Foundation, 00168 Rome, Italy.ORCID 0000-0003-2481-5354
Daniela PuglieseDepartment of Medical and Surgical Sciences, School of Medicine, Catholic University, 00168 Rome, Italy.ORCID 0000-0001-7930-5402
Giovanni MaconiGastroenterology Unit, Department Biomedical and Clinical Sciences, "L. Sacco" University Hospital, 20157 Milan, Italy.
Giovanni CatalettiGastroenterology Unit, Department Biomedical and Clinical Sciences, "L. Sacco" University Hospital, 20157 Milan, Italy.
Roberta PicaIBD Unit, Division of Gastroenterology, "S. Pertini" Hospital, 00157 Rome, Italy.ORCID 0000-0002-1097-9430
Claudio CassieriIBD Unit, Division of Gastroenterology, "S. Pertini" Hospital, 00157 Rome, Italy.
Edoardo Vincenzo SavarinoGastroenterology Unit, Azienda Ospedale-Università di Padova (AOUP), 35100 Padua, Italy.ORCID 0000-0002-3187-2894
Caterina De BarbaGastroenterology Unit, Azienda Ospedale-Università di Padova (AOUP), 35100 Padua, Italy.
Francesco CostaIBD Unit, Department of General Surgery and Gastroenterology, Pisa University Hospital, 56124 Pisa, Italy.ORCID 0000-0002-9150-3345
Linda CeccarelliIBD Unit, Department of General Surgery and Gastroenterology, Pisa University Hospital, 56124 Pisa, Italy.
Manuela MarzoDivision of Gastroenterology, "Veris-Delli Ponti" Hospital, 73020 Scorrano, Italy.
Walter EliseiDivision of Gastroenterology, A.O. "S. Camillo-Folanini", 00151 Rome, Italy.
Rita MonterubbianesiDivision of Gastroenterology, A.O. "S. Camillo-Folanini", 00151 Rome, Italy.
Roberto FaggianiDivision of Gastroenterology, A.O. "S. Camillo-Folanini", 00151 Rome, Italy.
Giovanni LombardiDivision of Gastroenterology, AORN "Cardarelli", 80131 Naples, Italy.
Marta PatturelliDivision of Gastroenterology, AORN "Cardarelli", 80131 Naples, Italy.
Davide Giuseppe RibaldoneIBD Unit, Department of Medical Sciences, Division of Gastroenterology, University of Turin, "A.O.U. Citta della Salute e della Scienza di Torino", 10126 Turin, Italy.ORCID 0000-0002-9421-3087
Lorenzo BertaniDivision of Gastroenterology, "Felice Lotti" Hospital, Azienda USL Toscana Nord Ovest, 56025 Pontedera, Italy.ORCID 0000-0001-8653-1790
Stefano RodinòDivision of Gastroenterology, "Ciaccio-Pugliese" Hospital, 88100 Catanzaro, Italy.
Ladislava SebkovaDivision of Gastroenterology, "Ciaccio-Pugliese" Hospital, 88100 Catanzaro, Italy.
Giorgia BodiniDepartment of Internal Medicine and Medical Specialties, Division of Gastroenterology, IRCCS "San Martino" Hospital, University of Genoa, 16132 Genoa, Italy.
Andrea PastaDepartment of Internal Medicine and Medical Specialties, Division of Gastroenterology, IRCCS "San Martino" Hospital, University of Genoa, 16132 Genoa, Italy.ORCID 0000-0003-1791-4506
Giuseppe PranzoAmbulatory for IBD Treatment, "Valle D'Itria" Hospital, 74015 Martina Franca, Italy.
Mariaelena SerioDivision of Gastroenterology, "San Salvatore" Hospital, 61121 Pesaro, Italy.
Antonella ScarcelliDivision of Gastroenterology, "San Salvatore" Hospital, 61121 Pesaro, Italy.
Ileana LuppinoDivision of Gastroenterology, "Annunziata" Hospital, 87100 Cosenza, Italy.
Antonio FerronatoDigestive Endoscopy Unit, ULSS7 Pedemontana, 36014 Santorso, Italy.ORCID 0009-0009-4890-1864
Rocco SpagnuoloDepartment of Health Science, University of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0002-0871-4644
Francesco LuzzaDepartment of Health Science, University of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0001-5120-1046
Antonietta Gerarda GravinaHepatogastroenterology and Digestive Endoscopy Unit, Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0001-8049-0115
Raffaele PellegrinoHepatogastroenterology and Digestive Endoscopy Unit, Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Giuliana VespereDivision of Gastroenterology, "Ospedale del Mare", ASL Na1, 80147 Naples, Italy.ORCID 0009-0007-1249-0309
Silvia SeddaDivision of Gastroenterology, "Ospedale del Mare", ASL Na1, 80147 Naples, Italy.
Vittorio D'OnofrioDivision of Gastroenterology, "Ospedale del Mare", ASL Na1, 80147 Naples, Italy.
Leonardo De LucaDivision of Gastroenterology, "Ospedale del Mare", ASL Na1, 80147 Naples, Italy.
Leonardo AllegrettaDivision of Gastroenterology, "Santa Caterina Novella" Hospital, 73013 Galatina, Italy.
Alessia Immacolata CazzatoDivision of Gastroenterology, "Santa Caterina Novella" Hospital, 73013 Galatina, Italy.
Libera FanigliuoloDivision of Gastroenterology, "S.S. Annunziata" Hospital, 74121 Taranto, Italy.
Laurino GrossiGastroenterology Unit, "Spirito Santo" Hospital, "G d'Annunzio" University, 65121 Pescara, Italy.ORCID 0000-0003-4654-0865
Fabio CortelliniDivision of Gastroenterology, "Infermi" Hospital, 47921 Rimini, Italy.
Giacomo FortiDivision of Digestive Endoscopy, "S. Maria Goretti" Hospital, 04100 Latina, Italy.
Paolo TontiDivision of Gastroenterology, "A. Perrino" Hospital, 72100 Brindisi, Italy.
Viviana NeveDivision of Gastroenterology, "A. Perrino" Hospital, 72100 Brindisi, Italy.
Simona PiergalliniIBD Unit, Division of Gastroenterology, "A. Murri" Hospital, 63900 Fermo, Italy.
Michela Di FonzoDivision of Gastroenterology, "Ospedale dei Castelli", 00072 Ariccia, Italy.
Federico IacopiniDivision of Gastroenterology, "Ospedale dei Castelli", 00072 Ariccia, Italy.ORCID 0000-0002-2371-5442
Pietro CaponeDivision of Gastroenterology, "T. Maresca" Hospital, 80059 Torre del Greco, Italy.
Federica GaianiGastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.ORCID 0000-0001-9615-0086
Stefano KayaliGastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.ORCID 0000-0003-4685-1276
Caterina MucherinoDivision of Gastroenterology, Azienda Ospedaliera "S. Anna e S. Sebastiano", 81100 Caserta, Italy.
Elvira D'AntonioDivision of Gastroenterology, Azienda Ospedaliera "S. Anna e S. Sebastiano", 81100 Caserta, Italy.
Laura MontesanoDivision of Gastroenterology, Azienda Ospedaliera "S. Anna e S. Sebastiano", 81100 Caserta, Italy.
Andrea CoccoIBD Unit, Division of Gastroenterology, "S. Pertini" Hospital, 00157 Rome, Italy.
Berardino D'AscoliDivision of Gastroenterology, "Madonna Delle Grazie" Hospital, 75100 Matera, Italy.
Raffaele ColucciDigestive Endoscopy Unit, "San Matteo Degli Infermi" Hospital, 06049 Spoleto, Italy.
Francesco BachettiDigestive Endoscopy Unit, "San Matteo Degli Infermi" Hospital, 06049 Spoleto, Italy.
Giorgia OrrùDepartment of Medical Sciences and Public Health, University of Cagliari, 09127 Cagliari, Italy.
Francesca Maria OnidiDivision of Gastroenterology, AORN "Brotzu" Hospital, 09134 Cagliari, Italy.
Paolo Usai SattaDivision of Gastroenterology, AORN "Brotzu" Hospital, 09134 Cagliari, Italy.ORCID 0000-0003-3344-927X
Marcello PicchioDivision of General Surgery, "P. Colombo" Hospital, ASL Roma 6, 00049 Velletri, Italy.ORCID 0000-0001-5070-8240
Alfredo PapaDepartment of Medical and Surgical Sciences, School of Medicine, Catholic University, 00168 Rome, Italy.ORCID 0000-0002-4186-7298

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

real liferemissionsafetyulcerative colitisupadacitinib

Identifiers

PMID41227197
PMCPMC12608937

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.