Evidence map›Paper›PMID 41226918›Full record

ArticleJournal of clinical medicine2025

Hybrid Assistive Limb Treatment for the Shoulder and Elbow Joints Enabled Recovery from Chronic-Phase Severe C5 Palsy Following Cervical Spine Surgery.

Yuichiro Soma, Shigeki Kubota, Hideki Kadone, Yukiyo Shimizu, Seioh Ezaki, Yasushi Hada, Yoshiyuki Sankai, Masashi Yamazaki

Abstract readCase Reports
In one paragraph

Article in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuichiro SomaDepartment of Orthopaedic Surgery, Institute of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan.ORCID 0009-0002-9970-9644
Shigeki KubotaDepartment of Orthopaedic Surgery, Institute of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan.ORCID 0000-0003-4455-4585
Hideki KadoneCenter for Innovating Medicine and Engineering (CIME), University of Tsukuba, Tsukuba 305-8575, Japan.ORCID 0000-0003-2953-6434
Yukiyo ShimizuDepartment of Rehabilitation Medicine, Institute of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan.ORCID 0000-0001-7491-4516
Seioh EzakiDepartment of Orthopaedic Surgery, Institute of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan.
Yasushi HadaDepartment of Rehabilitation Medicine, Institute of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan.ORCID 0000-0003-0292-3493
Yoshiyuki SankaiFaculty of Systems and Information Engineering, University of Tsukuba, Tsukuba 305-8575, Japan.
Masashi YamazakiDepartment of Orthopaedic Surgery, Institute of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan.ORCID 0000-0002-9293-3531

Funding

Shigeki Kubota 14060101-01
6 · The paper itself

Abstract

Postoperative C5 palsy is a common complication of cervical spine surgery. Inadequate recovery from C5 palsy can result in significant impairment of activities of daily living. However, no effective treatment has been established for persistent cases. In the present report, we describe a novel therapeutic approach using the Hybrid Assistive Limb (HAL) in a patient with severe, prolonged postoperative C5 palsy. The patient was a 46-year-old man who developed severe right C5 palsy following cervical spine surgery performed 41 months earlier. Despite undergoing conventional rehabilitation, no improvement was observed, and the muscle strength of the right deltoid and biceps remained at manual muscle testing (MMT) grade 2. HAL training, using both shoulder and elbow devices, was initiated at our institution. Training was conducted once weekly for a total of 106 sessions over 21 months. At baseline, the right shoulder range of motion was limited to 50° in flexion and 35° in abduction. With HAL-assisted training, flexion improved to 150° and abduction improved to 95° by the final (106th) session and further increased to 165° and 170°, respectively, at long-term follow-up. Deltoid strength, assessed using handheld dynamometry, increased from 3.5 Nm/kg at baseline to 28.5 Nm/kg after training. In this case, a long-term therapeutic program incorporating shoulder and elbow HAL training successfully improved severe and prolonged postoperative C5 palsy to a functionally useful level. This case highlights the potential effectiveness of HAL therapy for treatment-resistant postoperative C5 palsy.

Indexed as

C5 palsycervical spine surgeryelbow jointexoskeleton deviceshoulder joint

Identifiers

PMID41226918
PMCPMC12610387

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.