Evidence map›Paper›PMID 41226836›Full record

ArticleInternational journal of molecular sciences2025

Synthesis, Physicochemical Characterization, and Biocidal Evaluation of Three Novel Aminobenzoic Acid-Derived Schiff Bases Featuring Intramolecular Hydrogen Bonding.

Alexander Carreño, Vania Artigas, Belén Gómez-Arteaga, Evys Ancede-Gallardo, Marjorie Cepeda-Plaza, Jorge I Martínez-Araya, Roxana Arce, Manuel Gacitúa, Camila Videla, Marcelo Preite and 8 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Alexander CarreñoDepartamento de Ciencias Químicas, Facultad de Ciencias Exactas, Universidad Andres Bello, Av. República 275, Santiago 8370146, Chile.ORCID 0000-0001-9733-8224
Vania ArtigasLaboratorio de Síntesis Organometálica, Centro de Nanociencias Aplicadas (CANS), Facultad de Ciencias Exactas, Universidad Andres Bello, Av. República 330, Santiago 8370186, Chile.
Belén Gómez-ArteagaLaboratorio de Síntesis Organometálica, Centro de Nanociencias Aplicadas (CANS), Facultad de Ciencias Exactas, Universidad Andres Bello, Av. República 330, Santiago 8370186, Chile.
Evys Ancede-GallardoLaboratorio de Síntesis Organometálica, Centro de Nanociencias Aplicadas (CANS), Facultad de Ciencias Exactas, Universidad Andres Bello, Av. República 330, Santiago 8370186, Chile.ORCID 0000-0002-3478-6035
Marjorie Cepeda-PlazaDepartamento de Ciencias Químicas, Facultad de Ciencias Exactas, Universidad Andres Bello, Av. República 275, Santiago 8370146, Chile.
Jorge I Martínez-ArayaDepartamento de Ciencias Químicas, Facultad de Ciencias Exactas, Universidad Andres Bello, Av. República 275, Santiago 8370146, Chile.
Roxana ArceDepartamento de Ciencias Químicas, Facultad de Ciencias Exactas, Universidad Andres Bello, Av. República 275, Santiago 8370146, Chile.ORCID 0000-0002-1387-9232
Manuel GacitúaFacultad de Ingeniería y Ciencias, Universidad Diego Portales, Ejército 441, Santiago 8370191, Chile.ORCID 0000-0003-0807-2677
Camila VidelaLaboratorio de Síntesis Organometálica, Centro de Nanociencias Aplicadas (CANS), Facultad de Ciencias Exactas, Universidad Andres Bello, Av. República 330, Santiago 8370186, Chile.
Marcelo PreiteDepartamento de Química Orgánica, Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, Av. Vicuña Mackenna 4860, Santiago 7820436, Chile.
María Carolina OteroEscuela de Química y Farmacia, Facultad de Medicina, Universidad Andres Bello, Sazié 2320, Santiago 7591538, Chile.ORCID 0000-0002-8608-9813
Catalina GuerraLaboratorio de Hongos Fitopatógenos, Centro de Biotecnología Vegetal (CBV), Facultad de Ciencias de la Vida, Universidad Andres Bello, Av. República 330, Santiago 8370186, Chile.
Rubén PolancoLaboratorio de Hongos Fitopatógenos, Centro de Biotecnología Vegetal (CBV), Facultad de Ciencias de la Vida, Universidad Andres Bello, Av. República 330, Santiago 8370186, Chile.
Ignacio FuentesLaboratorio de Genética y Patogénesis Bacteriana, Centro de Investigación de Resiliencia a Pandemias, Facultad de Ciencias de la Vida, Universidad Andres Bello, República 330, Santiago 8370186, Chile.ORCID 0009-0005-2907-3080
Pedro MarchantLaboratorio de Genética y Patogénesis Bacteriana, Centro de Investigación de Resiliencia a Pandemias, Facultad de Ciencias de la Vida, Universidad Andres Bello, República 330, Santiago 8370186, Chile.
Osvaldo InostrozaSchool of Medicine, Faculty of Medicine, Universidad de los Andes, Santiago 7620001, Chile.ORCID 0000-0001-5950-974X
Fernando GilSchool of Medicine, Faculty of Medicine, Universidad de los Andes, Santiago 7620001, Chile.ORCID 0009-0006-1666-7987
Juan A FuentesLaboratorio de Genética y Patogénesis Bacteriana, Centro de Investigación de Resiliencia a Pandemias, Facultad de Ciencias de la Vida, Universidad Andres Bello, República 330, Santiago 8370186, Chile.ORCID 0000-0002-9374-0707

Funding

Fondo Nacional de Desarrollo Científico y Tecnológico 1220584Fondo Nacional de Desarrollo Científico y Tecnológico 1230917Fondo Nacional de Desarrollo Científico y Tecnológico 1250831Fondo Nacional de Desarrollo Científico y Tecnológico 1251136
6 · The paper itself

Abstract

Metal-free aminobenzoic acid-derived Schiff bases are attractive antimicrobial leads because their azomethine (-C=N-) functionality enables tunable electronic properties and target engagement. We investigated whether halogenation on the phenolic ring would modulate the redox behavior and enhance antibacterial potency, and hypothesized that heavier halogens would favorably tune physicochemical and electronic descriptors. We synthesized three derivatives (SB-3/Cl, SB-4/Br, and SB-5/I) and confirmed their structures using FTIR,

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsHydrogen BondingMicrobial Sensitivity TestsSchiff BasesAnti-Bacterial AgentsAnti-Infective AgentsSchiff Basesaminobenzoic acidbiocidal activitycyclic voltammetryhela cell viabilityintramolecular hydrogen bondingLHSMEPSchiff basesX-ray crystallography

Identifiers

PMID41226836
PMCPMC12608797

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.