Evidence map›Paper›PMID 41226820›Full record

ArticleInternational journal of molecular sciences2025

Promoter Frame Position Affects Strength and Nature of Circadian Oscillations in

Bhavna Kalyanaraman, Gabrielle Villafana, Stephanie R Taylor, Michelle E Farkas

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bhavna KalyanaramanDepartment of Chemistry, University of Massachusetts Amherst, Amherst, MA 01003, USA.ORCID 0000-0003-3652-4730
Gabrielle VillafanaMolecular and Cellular Biology Graduate Program, University of Massachusetts Amherst, Amherst, MA 01003, USA.
Stephanie R TaylorDepartment of Computer Science, Colby College, Waterville, ME 04901, USA.ORCID 0000-0003-3562-6479
Michelle E FarkasDepartment of Chemistry, University of Massachusetts Amherst, Amherst, MA 01003, USA.ORCID 0000-0001-5824-1243

Funding

Biotechnology Training Program in Applied Life SciencesT32GM135096 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Jeanne Ann Hardy, Ashish A. Kulkarni · 2020 to 2026
$3.9M
Chemical Biology Approaches for Studying Circadian RhythmsR35GM143016 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI FARKAS, MICHELLE ELIZABETH · 2021 to 2025
$1.9M
NIGMS NIH HHS R35 GM143016NIGMS NIH HHS T32 GM135096NIH HHS 3T32GM135096-24NIH HHS 5R35GM143016-24
6 · The paper itself

Abstract

The

Indexed as

Circadian ClocksCircadian RhythmGenes, ReporterLuciferasesPeriod Circadian ProteinsPromoter Regions, GeneticAnimalsCell Line, TumorHumansMiceLuciferasesPER2 protein, humanPeriod Circadian Proteinscircadian rhythmsfirefly luciferaselentiviral expressionPERIOD 2promoter-reporterrhythmicityU2OS cells

Identifiers

PMID41226820
PMCPMC12608312

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.