Evidence map›Paper›PMID 41226801›Full record

ArticleInternational journal of molecular sciences2025

Der p 23, A Frequent IgE Sensitizer in Humans, Induces Airway Inflammation in Mice.

Karen Donado, Luis Durango, Inés Benedetti, Nikolina Todorovic, Ronald Regino, Ana Lozano, Victoria Marrugo, Randy Reina, Dilia Mercado, Nathalie Acevedo and 5 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Karen DonadoInstitute for Immunological Research, University of Cartagena, Cartagena 130014, Colombia.ORCID 0000-0002-2644-9979
Luis DurangoInstitute for Immunological Research, University of Cartagena, Cartagena 130014, Colombia.
Inés BenedettiDepartment of Basic Sciences, School of Medicine, University of Cartagena, Cartagena 130014, Colombia.ORCID 0000-0002-6287-4470
Nikolina TodorovicInstitute of Molecular Biosciences, Structural Biology and Biophysics, University of Graz, 8010 Graz, Austria.ORCID 0000-0003-4550-5742
Ronald ReginoInstitute for Immunological Research, University of Cartagena, Cartagena 130014, Colombia.ORCID 0000-0002-6731-6136
Ana LozanoInstitute for Immunological Research, University of Cartagena, Cartagena 130014, Colombia.ORCID 0000-0002-6553-3110
Victoria MarrugoInstitute for Immunological Research, University of Cartagena, Cartagena 130014, Colombia.ORCID 0009-0005-0470-8799
Randy ReinaInstitute for Immunological Research, University of Cartagena, Cartagena 130014, Colombia.
Dilia MercadoInstitute for Immunological Research, University of Cartagena, Cartagena 130014, Colombia.
Nathalie AcevedoInstitute for Immunological Research, University of Cartagena, Cartagena 130014, Colombia.ORCID 0000-0002-5154-2964
Josefina ZakzukInstitute for Immunological Research, University of Cartagena, Cartagena 130014, Colombia.ORCID 0000-0002-6007-5376
Enrique Fernández-CaldasDivision of Allergy and Immunology, Department of Internal Medicine, University of South Florida Morsani College of Medicine, Tampa, FL 33613, USA.
Walter KellerInstitute of Molecular Biosciences, Structural Biology and Biophysics, University of Graz, 8010 Graz, Austria.ORCID 0000-0002-2261-958X
Leonardo PuertaInstitute for Immunological Research, University of Cartagena, Cartagena 130014, Colombia.ORCID 0000-0003-2246-9697
Luis CaraballoInstitute for Immunological Research, University of Cartagena, Cartagena 130014, Colombia.ORCID 0000-0002-5204-1109

Funding

Sistema General de Regalías BPIN2020000100405
6 · The paper itself

Abstract

Der p 23 induces a high-frequency sensitization in allergic individuals. However, its allergenic activity and clinical impact are scarce. We aimed to evaluate the ability of rDer p 23 to induce allergic inflammation in a mouse model and to test IgE reactivity in humans. Female Balb/c mice were sensitized and challenged with rDer p 23 and

Indexed as

AllergensAntigens, DermatophagoidesArthropod ProteinsAsthmaImmunoglobulin EInflammationAdultAnimalsBronchial HyperreactivityBronchoalveolar Lavage FluidCytokinesDermatophagoides pteronyssinusDisease Models, AnimalFemaleHumansLungAllergensAntigens, DermatophagoidesArthropod ProteinsCytokinesImmunoglobulin Eairway inflammationallergyanimal modelasthmaDer p 23house dust miteIgE-sensitization

Identifiers

PMID41226801
PMCPMC12609036

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.