Evidence map›Paper›PMID 41226754›Full record

ArticleInternational journal of molecular sciences2025

Antibodies to Periodontal Bacteria Are Associated with Systemic Lupus Erythematosus and Autoantibody Positivity.

Laura Massarenti, Henrik Christian Bidstrup Leffers, Thorsten Brodersen, Peter Riis Hansen, Christian Damgaard, Ole Birger Pedersen, Søren Jacobsen, Claus Henrik Nielsen

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Laura MassarentiInstitute for Inflammation Research, Center for Rheumatology and Spine Diseases, Section 7521, Copenhagen University Hospital Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0001-5647-4617
Henrik Christian Bidstrup LeffersCopenhagen Center for Autoimmune Connective Tissue Diseases (COPEACT), Center for Rheumatology and Spine Diseases, Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0001-5821-2768
Thorsten BrodersenDepartment of Clinical Immunology, Zealand University Hospital, 4600 Køge, Denmark.ORCID 0000-0003-4431-9972
Peter Riis HansenDepartment of Cardiology, Herlev-Gentofte Hospital, 2900 Hellerup, Denmark.ORCID 0000-0002-9056-535X
Christian DamgaardResearch Area Periodontology, Section for Oral Biology and Immunopathology, Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.ORCID 0000-0003-2394-746X
Ole Birger PedersenDepartment of Clinical Immunology, Zealand University Hospital, 4600 Køge, Denmark.ORCID 0000-0003-2312-5976
Søren JacobsenCopenhagen Center for Autoimmune Connective Tissue Diseases (COPEACT), Center for Rheumatology and Spine Diseases, Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0002-5654-4993
Claus Henrik NielsenInstitute for Inflammation Research, Center for Rheumatology and Spine Diseases, Section 7521, Copenhagen University Hospital Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0001-7543-9016

Funding

Danmarks Frie Forskningsfond DFF - 7016-00233
6 · The paper itself

Abstract

Periodontitis has been suggested to play a role in the etiology of systemic lupus erythematosus (SLE). However, evidence remains limited, and the underlying mechanisms are unclear.

Indexed as

Antibodies, BacterialAutoantibodiesLupus Erythematosus, SystemicPeriodontitisPorphyromonas gingivalisAdultAggregatibacter actinomycetemcomitansCase-Control StudiesFemaleHumansImmunoglobulin GMaleMiddle AgedAntibodies, BacterialAutoantibodiesImmunoglobulin GAggregatibacter actinomycetemcomitansautoantibodiesperiodontitisPorphyromonas gingivalissmokingsystemic lupus erythematosus

Identifiers

PMID41226754
PMCPMC12609766

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.