Evidence map›Paper›PMID 41226733›Full record

ArticleInternational journal of molecular sciences2025

Kim Ngan Luu Hoang, Shelley Evans, Thomas W Willis, Kate Davies, Hannah Kockelbergh, Lee Silcock, Kim Piechocki, Anna Fowler, Elizabeth J Soilleux

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kim Ngan Luu HoangDepartment of Pathology, University of Cambridge, Cambridge CB2 1TN, UK.ORCID 0000-0001-5670-1832
Shelley EvansDepartment of Pathology, University of Cambridge, Cambridge CB2 1TN, UK.ORCID 0000-0003-3242-6017
Thomas W WillisMedical Research Council Biostatistics Unit, University of Cambridge, Cambridge CB2 1TN, UK.ORCID 0000-0001-6138-3496
Kate DaviesDepartment of Pathology, University of Cambridge, Cambridge CB2 1TN, UK.ORCID 0000-0002-9807-1231
Hannah KockelberghDepartment of Health Data Science, University of Liverpool, Liverpool L69 7ZX, UK.
Lee SilcockNonacus Ltd., Quinton Business Park, Birmingham B32 1AF, UK.
Kim PiechockiNonacus Ltd., Quinton Business Park, Birmingham B32 1AF, UK.
Anna FowlerDepartment of Health Data Science, University of Liverpool, Liverpool L69 7ZX, UK.
Elizabeth J SoilleuxDepartment of Pathology, University of Cambridge, Cambridge CB2 1TN, UK.ORCID 0000-0002-4032-7249

Funding

Coeliac UK Sponsored DissertationCoeliac UK and Innovate UK INOV01-18Department of Pathology, University of Cambridge PhD scholarshipNIHR Cambridge Biomedical Research Centre NIHR203312
6 · The paper itself

Abstract

Coeliac disease (CeD) is a gastrointestinal enteropathy triggered by the consumption of gluten in predisposed individuals. A recent study showed that individuals were at more than 10% risk of having CeD if a first-degree relative also had the disease. However, only around 50% of CeD genetic heritability is attributable to specific loci, with the majority of this heritable risk attributed to the

Indexed as

ButyrophilinsCeliac DiseaseGenetic LociGenetic Predisposition to DiseaseAdultCase-Control StudiesComputer SimulationFemaleHumansMaleMiddle AgedPolymorphism, Single NucleotideButyrophilinsbutyrophilin familycoeliac diseasehypervariable region 4 (HV4)UK Biobank

Identifiers

PMID41226733
PMCPMC12610073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.