Evidence map›Paper›PMID 41226704›Full record

ArticleInternational journal of molecular sciences2025

Assessment of AOPP, TBARS, and Inflammatory Status in Diabetic Nephropathy and Hemodialyzed Patients.

Daniel Cosmin Caragea, Lidia Boldeanu, Mohamed-Zakaria Assani, Mariana-Emilia Caragea, Alexandra-Ștefania Stroe-Ionescu, Romeo Popa, Daniela-Teodora Maria, Vlad Pădureanu, Cristin Constantin Vere, Mihail Virgil Boldeanu

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daniel Cosmin CarageaDepartment of Nephrology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Lidia BoldeanuDepartment of Microbiology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0002-4817-1365
Mohamed-Zakaria AssaniDoctoral School, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0009-0009-3146-8769
Mariana-Emilia CarageaDoctoral School, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Alexandra-Ștefania Stroe-IonescuDoctoral School, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Romeo PopaDepartment of Pharmacology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Daniela-Teodora MariaDepartment of Nephrology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0009-0000-3410-1334
Vlad PădureanuDepartment of Internal Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0001-7398-5689
Cristin Constantin VereDepartment of Gastroenterology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Mihail Virgil BoldeanuDepartment of Immunology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0003-2481-6138

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We compared oxidative markers and their links to inflammation in diabetic nephropathy and hemodialysis to identify independent determinants. We studied 180 adults, 90 patients with type 2 diabetes and diabetic nephropathy and 90 patients on hemodialysis. We measured serum advanced oxidation protein products (AOPP) and thiobarbituric acid reactive substances (TBARS) by enzyme-linked immunosorbent assay (ELISA). Partial correlations were adjusted for age, sex, and albumin with false discovery rate (FDR) control. Principal component analysis (PCA) summarized inflammatory indices and linear models tested predictors of AOPP and TBARS. Oxidative damage was higher in hemodialysis, with AOPP median 25.80 versus 5.06 and TBARS 8.49 versus 1.89,

Indexed as

Advanced Oxidation Protein ProductsDiabetic NephropathiesInflammationRenal DialysisThiobarbituric Acid Reactive SubstancesAdultAgedBiomarkersC-Reactive ProteinDiabetes Mellitus, Type 2FemaleHumansMaleMiddle AgedOxidative StressAdvanced Oxidation Protein ProductsBiomarkersC-Reactive ProteinThiobarbituric Acid Reactive SubstancesAOPPchronic kidney diseasediabetic nephropathyhemodialysisinflammationoxidative stressTBARS

Identifiers

PMID41226704
PMCPMC12609688

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.