Evidence map›Paper›PMID 41226544›Full record

ArticleInternational journal of molecular sciences2025

Positive and Negative Symptoms of Schizophrenia and Polymorphic Variants of the

Svetlana A Ivanova, Vladimir V Tiguntsev, Anastasia S Boiko, Ekaterina V Mikhalitskaya, Dmitry A Petkun, Irina A Mednova, Olga Yu Fedorenko, Nikolay A Skryabin, Elena G Kornetova, Alexander N Kornetov and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Svetlana A IvanovaMental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634014, Russia.ORCID 0000-0001-7078-323X
Vladimir V TiguntsevMental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634014, Russia.
Anastasia S BoikoMental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634014, Russia.ORCID 0000-0002-2955-9057
Ekaterina V MikhalitskayaMental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634014, Russia.ORCID 0000-0001-7085-2741
Dmitry A PetkunMental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634014, Russia.ORCID 0009-0008-1878-5084
Irina A MednovaMental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634014, Russia.ORCID 0000-0002-8057-3305
Olga Yu FedorenkoMental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634014, Russia.ORCID 0000-0002-9565-6314
Nikolay A SkryabinResearch Institute of Medical Genetics, Tomsk National Research Medical Center of the Russian Academy of Sciences, Tomsk 634050, Russia.ORCID 0000-0002-2491-3141
Elena G KornetovaMental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634014, Russia.ORCID 0000-0002-5179-9727
Alexander N KornetovMental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634014, Russia.ORCID 0000-0002-2342-7504
Nikolay A BokhanMental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk 634014, Russia.

Funding

Tomsk National Research Medical Center #24/2-grant - MNI
6 · The paper itself

Abstract

The role of the genetic component in the development of schizophrenia and the formation of its clinical heterogeneity has been proven. To conduct a pilot associative analysis between positive and negative schizophrenia symptoms and polymorphic variants of the Transcription Factor 4 (

Indexed as

Genetic Predisposition to DiseasePolymorphism, Single NucleotideSchizophreniaTranscription Factor 4AdultAllelesCase-Control StudiesFemaleGene FrequencyGenotypeHumansMaleMiddle AgedPilot ProjectsTCF4 protein, humanTranscription Factor 4clinical heterogeneitymolecular geneticsschizophreniasingle nucleotide polymorphismTCF4

Identifiers

PMID41226544
PMCPMC12609942

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.