ArticleInternational journal of molecular sciences2025
Role of Myeloid Cell Glucose Transporter 1 in the Host Response During Pneumonia Caused by
Liza Pereverzeva, Valentine Léopold, Anno Saris, Alex R Schuurman, Joe M Butler, Tom D Y Reijnders, Joris J T H Roelofs, Daniël R Faber, W Joost Wiersinga, Cornelis Van't Veer and 2 more
Abstract read
In one paragraphArticle in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
12 authors.
Liza PereverzevaCenter for Infection and Molecular Medicine, Amsterdam University Medical Center, University of Amsterdam, 1105AZ Amsterdam, The Netherlands.ORCID 0000-0001-9091-7506 Valentine LéopoldCenter for Infection and Molecular Medicine, Amsterdam University Medical Center, University of Amsterdam, 1105AZ Amsterdam, The Netherlands.
Anno SarisCenter for Infection and Molecular Medicine, Amsterdam University Medical Center, University of Amsterdam, 1105AZ Amsterdam, The Netherlands.ORCID 0000-0003-0493-9501 Alex R SchuurmanCenter for Infection and Molecular Medicine, Amsterdam University Medical Center, University of Amsterdam, 1105AZ Amsterdam, The Netherlands.
Joe M ButlerCenter for Infection and Molecular Medicine, Amsterdam University Medical Center, University of Amsterdam, 1105AZ Amsterdam, The Netherlands.
Tom D Y ReijndersCenter for Infection and Molecular Medicine, Amsterdam University Medical Center, University of Amsterdam, 1105AZ Amsterdam, The Netherlands.
Joris J T H RoelofsDepartment of Pathology, Amsterdam University Medical Center, University of Amsterdam, 1105AZ Amsterdam, The Netherlands.ORCID 0000-0001-9595-6571 Daniël R FaberBovenIJ Hospital, 1034CS Amsterdam, The Netherlands.
W Joost WiersingaCenter for Infection and Molecular Medicine, Amsterdam University Medical Center, University of Amsterdam, 1105AZ Amsterdam, The Netherlands.
Cornelis Van't VeerCenter for Infection and Molecular Medicine, Amsterdam University Medical Center, University of Amsterdam, 1105AZ Amsterdam, The Netherlands.
Alex F de VosCenter for Infection and Molecular Medicine, Amsterdam University Medical Center, University of Amsterdam, 1105AZ Amsterdam, The Netherlands.ORCID 0000-0002-2472-3014 Tom van der PollCenter for Infection and Molecular Medicine, Amsterdam University Medical Center, University of Amsterdam, 1105AZ Amsterdam, The Netherlands.
Funding
the Netherlands Organization for Health Research and Development, ZonMW, program JPIAMR 547001008
6 · The paper itselfAbstract
During infection, myeloid cells are subjected to a fast increase in energy demand. Glucose transporter 1 (GLUT1) is a key mediator of glucose metabolism, especially for glycolysis. The present study aimed to investigate GLUT1 expression in monocytes and neutrophils from patients with community-acquired pneumonia (CAP) and to determine the functional role of GLUT1 in the responsiveness during pneumonia evoked in mice by
Indexed as
Glucose Transporter Type 1Myeloid CellsPneumonia, PneumococcalStreptococcus pneumoniaeAgedAnimalsCommunity-Acquired InfectionsFemaleHumansLungMaleMiceMice, Inbred C57BLMice, KnockoutMiddle AgedMonocytesGlucose Transporter Type 1SLC2A1 protein, humanbacterial infectionexperimental pneumonia modelGLUTsimmune responsemacrophagesmicemonocytesneutrophils
Identifiers
PMID41226500
PMCPMC12609635
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