Evidence map›Paper›PMID 41226358›Full record

ReviewInternational journal of molecular sciences2025

Matrix Metalloproteinases in Inflammatory Dermatoses.

Joanna Czerwińska, Agnieszka Owczarczyk-Saczonek

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Joanna CzerwińskaDepartment of Dermatology, Sexually Transmitted Diseases and Clinical Immunology, School of Medicine, Collegium Medicum, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.ORCID 0000-0001-6371-8130
Agnieszka Owczarczyk-SaczonekDepartment of Dermatology, Sexually Transmitted Diseases and Clinical Immunology, School of Medicine, Collegium Medicum, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland.ORCID 0000-0002-8372-0438

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Matrix metalloproteinases (MMPs) are endopeptidases that help maintain tissue homeostasis. Dysregulation of MMP secretion or activity, along with issues in their natural regulators, contributes to the development of many disorders, including autoimmune skin diseases. This article provides a comprehensive review of current research on MMP biology, their physiological functions, and disease-specific evidence in dermatology. Based on available English-language studies, we discuss key papers with important findings and the latest systematic reviews from PubMed. Additionally, a comparison, synthesis, and summary of reported results are included to highlight the specific role of MMPs in dermatology and to identify research gaps that need to be addressed for developing and using MMPs as potential biomarkers in skin disease pathophysiology.

Indexed as

InflammationMatrix MetalloproteinasesSkin DiseasesAnimalsBiomarkersHumansBiomarkersMatrix Metalloproteinasesalopecia areataatopic dermatitisblistering diseasesinflammatory skin disordersmetalloproteinasesprurigo nodularispsoriasisscleroderma

Identifiers

PMID41226358
PMCPMC12610149

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.