Novel Dual-Coenzyme Specificity and Thermostability of Malate Dehydrogenase Identified in the Cyanobacterium

Yadong Ge, Yifan Wu, Bo Zhou, Xiaojie Wu, Yu Ren, Jialin Zhu, Yali Ge

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yadong GeAnhui Provincial Key Laboratory of Molecular Enzymology and Mechanism of Major Metabolic Diseases, College of Life Sciences, Anhui Normal University, Wuhu 241002, China.

Yifan WuAnhui Provincial Key Laboratory of Molecular Enzymology and Mechanism of Major Metabolic Diseases, College of Life Sciences, Anhui Normal University, Wuhu 241002, China.

Bo ZhouSchool of Ecology and Environment, Anhui Normal University, Wuhu 241002, China.

Xiaojie WuSchool of Ecology and Environment, Anhui Normal University, Wuhu 241002, China.

Yu RenSchool of Ecology and Environment, Anhui Normal University, Wuhu 241002, China.

Jialin ZhuSchool of Ecology and Environment, Anhui Normal University, Wuhu 241002, China.

Yali GeSchool of Ecology and Environment, Anhui Normal University, Wuhu 241002, China.

Funding

National Natural Science Foundation of China 32070463the Outstanding Innovative Research Team for Molecular Enzymology and Detection in Anhui Provincial Universities 2022AH010012

6 · The paper itself

Abstract

Malate dehydrogenase (MDH) is a key energy metabolic enzyme with distinct coenzyme specificity for either NAD

Indexed as

Bacterial ProteinsCoenzymesMalate DehydrogenaseMicrocystisAmino Acid SequenceEnzyme StabilityHydrogen-Ion ConcentrationKineticsModels, MolecularNADNADPSubstrate SpecificityTemperatureBacterial ProteinsCoenzymesMalate DehydrogenaseNADNADPcyanobacteriadual coenzyme specificityenzymatic characterizationkineticsmalate dehydrogenaseMicrocystis aeruginosa PCC7806molecular evolutionthermostability

Identifiers

PMID41226353

DOI10.3390/ijms262110313

PMCPMC12609799

What OpenQuestion holds

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.