Evidence map›Paper›PMID 41226296›Full record

ArticleInternational journal of molecular sciences2025

Preparation and Characterization of New pH-Sensitive Polyurethane Hydrogels as Anti-Cancer Drug Delivery Systems for 5-Fluorouracyl and Fluorodeoxyuridine.

Marcin Sobczak, Adam Kasiński, Karolina Kędra, Joachim Frankowski, Matylda Kurzątkowska, Karolina Watrakiewicz, Karolina Mulas, Katarzyna Strzelecka, Marcin Chodkowski, Małgorzata Krzyżowska and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Marcin SobczakDepartment of Pharmaceutical Chemistry and Biomaterials, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1 Str., 02-097 Warsaw, Poland.ORCID 0000-0002-7362-8881
Adam KasińskiDepartment of Pharmaceutical Chemistry and Biomaterials, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1 Str., 02-097 Warsaw, Poland.ORCID 0000-0003-0187-9638
Karolina KędraInstitute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52 Str., 01-224 Warsaw, Poland.ORCID 0000-0002-3696-1618
Joachim FrankowskiDepartment of Pharmaceutical Chemistry and Biomaterials, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1 Str., 02-097 Warsaw, Poland.ORCID 0009-0002-8983-7212
Matylda KurzątkowskaDepartment of Pharmaceutical Chemistry and Biomaterials, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1 Str., 02-097 Warsaw, Poland.
Karolina WatrakiewiczDepartment of Pharmaceutical Chemistry and Biomaterials, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1 Str., 02-097 Warsaw, Poland.ORCID 0009-0006-8745-628X
Karolina MulasDepartment of Pharmaceutical Chemistry and Biomaterials, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1 Str., 02-097 Warsaw, Poland.
Katarzyna StrzeleckaDepartment of Pharmaceutical Chemistry and Biomaterials, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1 Str., 02-097 Warsaw, Poland.ORCID 0000-0001-6260-8423
Marcin ChodkowskiDivision of Medical and Environmental Microbiology, Military Institute of Hygiene and Epidemiology, 01-063 Warsaw, Poland.
Małgorzata KrzyżowskaDivision of Medical and Environmental Microbiology, Military Institute of Hygiene and Epidemiology, 01-063 Warsaw, Poland.ORCID 0000-0002-8409-3974
Andrzej DeptałaDepartment of Oncology, National Medical Institute of the Ministry of the Interior and Administration, 02-507 Warsaw, Poland.ORCID 0000-0003-2640-2043
Ewa OledzkaDepartment of Pharmaceutical Chemistry and Biomaterials, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1 Str., 02-097 Warsaw, Poland.ORCID 0000-0003-0660-3315

Funding

Medical Research Agency 2024/ABM/03/KPO/KPOD.07.07-IW.07-0211/24-00
6 · The paper itself

Abstract

In this study, non-toxic, biodegradable, and pH-sensitive polyurethane hydrogels (PUs) were prepared by using hexamethylene diisocyanate (HDI), copolymers of є-caprolactone (CL),

Indexed as

Antineoplastic AgentsDrug CarriersDrug Delivery SystemsFluorouracilHydrogelsPolyurethanesCell Line, TumorDrug LiberationHumansHydrogen-Ion ConcentrationPolyethylene GlycolsAntineoplastic AgentsDrug CarriersFluorouracilHydrogelsPolyethylene GlycolsPolyurethanesanti-cancer drugbiomedical hydrogelbiomedical polyestersbiomedical polyurethanecontrolled anti-cancer drug releasedrug delivery systems

Identifiers

PMID41226296
PMCPMC12609683

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.