ArticleMolecules (Basel, Switzerland)2025
Associations of Omega-3 and Omega-6 Fatty Acids Intake with Visceral Adiposity: Sex-Specific Patterns in a Population-Based Study.
Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
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7 authors.
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Abstract
backgroundObesity is a disease with high prevalence worldwide, and the accumulation of visceral fat is related to increased cardiovascular risk. The inclusion of polyunsaturated fatty acids (PUFAs) in the diet has been shown to be a promising nutritional strategy. We aimed to examine the associations between PUFAs consumption and visceral adiposity dysfunction, assessed by the visceral adiposity index (VAI).
methodsThis cross-sectional study included 697 adults from the SHIP-Brazil cohort. Structured interviews collected sociodemographic, lifestyle, and dietary data. The intake of omega-3, omega-6, EPA, DHA, and EPA + DHA intake assessed through an adapted food frequency questionnaire (FFQ) was categorized into tertiles. Serum lipids were analyzed using the Cobas system, and VAI was calculated by a sex-specific formula and categorized into two groups (low and high VAI, p50), according to sex.
resultsAmong men, a higher VAI was associated with greater energy intake and higher carbohydrate and fat consumption. Among women, EPA + DHA intake (β = -0.396, 95% CI: -0.639; -0.152,
conclusionsThe EPA + DHA intake, EPA, and DHA intake were inversely associated with VAI in women, but not in men. Omega-6 intake was negatively associated with VAI in men and positively associated with VAI in women. It is important to highlight that, given the cross-sectional design, these associations do not establish temporality or causality.
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