Evidence map›Paper›PMID 41226137›Full record

ArticleMolecules (Basel, Switzerland)2025

Zinc-Modified Mordenite Zeolite as a Molecular Carrier for Donepezil: A Framework for Drug Delivery Applications.

Diana Guaya, Lupe Carolina Espinoza, Ximena Jaramillo-Fierro, Dagmar Gualotuña Campoverde, Lilian Sosa, Ana Cristina Calpena

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Diana GuayaDepartament of Chemistry, Universidad Técnica Particular de Loja, Loja 1101608, Ecuador.ORCID 0000-0002-5872-7208
Lupe Carolina EspinozaDepartament of Chemistry, Universidad Técnica Particular de Loja, Loja 1101608, Ecuador.ORCID 0000-0003-1486-5622
Ximena Jaramillo-FierroDepartament of Chemistry, Universidad Técnica Particular de Loja, Loja 1101608, Ecuador.ORCID 0000-0002-3136-4419
Dagmar Gualotuña CampoverdeCarrera de Bioquímica y Farmacia, Universidad Técnica Particular de Loja (UTPL), Calle París s/n y Praga, Loja 110107, Ecuador.
Lilian SosaInstitute of Microbiology Research (IIM), Faculty of Sciences, National Autonomous University of Honduras (UNAH), Tegucigalpa 11101, Honduras.ORCID 0000-0001-8148-9482
Ana Cristina CalpenaDepartment of Pharmacy, Pharmaceutical Technology and Physical Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain.ORCID 0000-0002-4989-4821

Funding

Universidad Técnica Particular de Loja (UTPL) PROY_INV_QU_2022_3585
6 · The paper itself

Abstract

The development of advanced drug delivery systems is essential for improving therapeutic efficacy, particularly in the treatment of neurodegenerative disorders such as Alzheimer's disease. This study investigates zinc-modified mordenite zeolite (MR-ZN) as a novel platform for the controlled delivery of donepezil (DPZ), a cholinesterase inhibitor. Natural mordenite was modified with zinc, enhancing its surface area from 62.1 to 85.4 m

Indexed as

DonepezilDrug CarriersDrug Delivery SystemsZeolitesZincAdsorptionCholinesterase InhibitorsDrug LiberationHydrogen BondingKineticsCholinesterase InhibitorsDonepezilDrug CarriersZeolitesZinccontrolled releasedonepezildrug carrierszinc-modified mordenite

Identifiers

PMID41226137
PMCPMC12610327

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.