Evidence map›Paper›PMID 41226136›Full record

ReviewMolecules (Basel, Switzerland)2025

Extraction, Purification, Structure, and Bioactivities of Polysaccharides from

Zhenni Qu, Qi Gao, Menghan Liu, Qiang Zhang, Dianhua Shi, Peng Gao, Yanpeng Dai

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhenni QuShandong Academy of Chinese Medicine, Jinan 250014, China.
Qi GaoShandong Academy of Chinese Medicine, Jinan 250014, China.
Menghan LiuShandong Academy of Chinese Medicine, Jinan 250014, China.
Qiang ZhangShandong Academy of Chinese Medicine, Jinan 250014, China.
Dianhua ShiShandong Academy of Chinese Medicine, Jinan 250014, China.
Peng GaoInstitute of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Yanpeng DaiShandong Academy of Chinese Medicine, Jinan 250014, China.

Funding

the Science and Technology Co-construction Project of the State Administration of Traditional Chinese Medicine's Science and Technology Department GZY-KJS-SD-2024-055the Shandong Province Science and Technology Project for Traditional Chinese Medicine M20242210the Shandong Province Science and Technology Project for Traditional Chinese Medicine Q2023199the Shandong Provincial Key Research and Development Program (Major Scientific and Technological Innovation Project) 2024CXGC010619
6 · The paper itself

Abstract

ethnopharmacological relevanceAIM OF THE STUDY: This review aims to provide the latest and the most comprehensive information on GLPs, specifically investigating their extraction technologies, isolation and purification methods, structural characteristics, and pharmacological activities of GLPs. It seeks to lay a foundation for further investigating pharmacological activities and application scope and guide the safe clinical practice of GLPs. MATERIALS AND

methodsPubMed, Google Scholar, Web of Science, Elsevier, China National Knowledge Infrastructure (CNKI), and other online databases were used to collect literature about extraction, isolation, and purification methods, structural characteristics, and pharmacological activities of GLPs published before January 2025.

resultsPolysaccharides are the main active ingredient of GL. Currently, 19 types of GLPs have been extracted. Methods of extracting GL include hot water extraction, ultrasound-assisted extraction, and enzyme extraction. The most frequently used method of separation and purification within GLP is column chromatography, often entailing cellulose column chromatography and ion exchange chromatography. GLPs have various pharmacological activities, including immunomodulatory, antioxidant, and antitumor.

conclusionsWhile GLPs show promising immunomodulatory and antitumor effects, elucidating their structure-activity relationships is essential for advancing our understanding and requires future research.

Indexed as

ApiaceaePlant ExtractsPolysaccharidesAnimalsAntioxidantsHumansAntioxidantsPlant ExtractsPolysaccharidesextractionglehnia littoralispharmacological activitiespolysaccharidespurificationstructural characteristics

Identifiers

PMID41226136
PMCPMC12610580

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.