Evidence map›Paper›PMID 41225791›Full record

ArticlePlants (Basel, Switzerland)2025

Bioactive Glycosylated Flavonoids Exhibiting LXR Agonist Activity from a Lauraceae Colombian Species.

Juanita Pulido-Teuta, Fabian López-Vallejo, Adrián G Sandoval-Hernández, Carlos-Eduardo Narváez-Cuenca, Mónica Avila-Murillo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Juanita Pulido-TeutaQuiProNaB, Departamento de Química, Facultad de Ciencias, Universidad Nacional de Colombia, Sede Bogotá, Carrera 30 No 45-03, Bogotá 111321, Colombia.
Fabian López-VallejoQuiProNaB, Departamento de Química, Facultad de Ciencias, Universidad Nacional de Colombia, Sede Bogotá, Carrera 30 No 45-03, Bogotá 111321, Colombia.ORCID 0000-0002-5802-9530
Adrián G Sandoval-HernándezGrupo de Muerte Celular, Instituto de Genética, Universidad Nacional de Colombia, Sede Bogotá, Carrera 30 No 45-03, Bogotá 111321, Colombia.
Carlos-Eduardo Narváez-CuencaFood Chemistry Research Group, Departamento de Química, Facultad de Ciencias, Universidad Nacional de Colombia, Sede Bogotá, Carrera 30 No 45-03, Bogotá 111321, Colombia.ORCID 0000-0002-9510-6881
Mónica Avila-MurilloQuiProNaB, Departamento de Química, Facultad de Ciencias, Universidad Nacional de Colombia, Sede Bogotá, Carrera 30 No 45-03, Bogotá 111321, Colombia.ORCID 0000-0003-0859-8353

Funding

Ministerio de Ciencia, Tecnología e Innovación 727 y 734 de 2018
6 · The paper itself

Abstract

Lipid metabolism is a vital biological process essential for human health, encompassing key pathways necessary for the survival and homeostasis of all organisms. Liver X Receptors (LXRs) are extensively acknowledged as pivotal regulators of lipid homeostasis and inflammatory responses. Pharmacological activation of Liver X Receptor (LXR) has been shown to increase expression of ApoE and ABCA1 proteins, reducing neurodegeneration in murine models of Alzheimer's disease. Because previous reports determined that

Indexed as

agonistic activityglycosylated flavonoidsinflammatory responseliver X receptorsmolecular dockingNectandra

Identifiers

PMID41225791
PMCPMC12608195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.