Evidence map›Paper›PMID 41225687›Full record

ReviewPerioperative medicine (London, England)2025

The imperative integration of patient blood management into ERACS: bridging the gap for optimizing outcomes in cardiac surgery.

Gabrielle Barbosa Borgomoni, Fábio Antônio Serra de Lima Júnior, Omar Asdrúbal Vilca Mejia, Fábio Biscegli Jatene

Abstract readReview
In one paragraph

Review in Perioperative medicine (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gabrielle Barbosa BorgomoniUnidade Cirurgica de Qualidade E Seguranca e Departamento de Cirurgia Cardiovascular, Instituto Do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil. gabrielle.barbosa@hc.fm.usp.br.
Fábio Antônio Serra de Lima JúniorUnidade Cirurgica de Qualidade E Seguranca e Departamento de Cirurgia Cardiovascular, Instituto Do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.
Omar Asdrúbal Vilca MejiaUnidade Cirurgica de Qualidade E Seguranca e Departamento de Cirurgia Cardiovascular, Instituto Do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.
Fábio Biscegli JateneUnidade Cirurgica de Qualidade E Seguranca e Departamento de Cirurgia Cardiovascular, Instituto Do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnhanced Recovery After Surgery (ERAS) in cardiac surgery was designed to improve outcomes, reduce complications, and optimize recovery. Despite these efforts, perioperative anemia, a key modifiable risk factor that affects 20 to 41% of patients, remains under-addressed and is strongly associated with increased transfusion rates, morbidity, and mortality. Patient Blood Management (PBM) has demonstrated efficacy in improving outcomes by optimizing hemoglobin levels, reducing blood loss, and minimizing transfusions, although it is not yet fully integrated into cardiac ERAS pathways. MAIN TEXT: ERAS pathways are patient-centered, multidisciplinary, preventive and evidence-based. Although the principles of PBM align with ERAS, detailed PBM targets are often neglected in ERAS-based line of care. In cardiac surgery, the risks associated with anemia and transfusion are substantially higher than in other surgical specialties. However, perioperative interventions might manage anemia, mitigate bleeding risks, and improve tolerance to anemia in this particularly sensitive population. Implementation challenges include the need for institutional culture shifts and multidisciplinary education maintaining clinical awareness to support individualized recovery trajectories.

conclusionIntegrating PBM into cardiac ERAS-based pathways addresses a critical gap that could lead to improved patient outcomes, reduced complications, lower transfusion rates, and optimized resource utilization. While healthcare progressively focuses on safety, quality, and value-based care, the convergence of ERAS and PBM offers a comprehensive approach to advancing perioperative medicine in cardiac surgery.

Indexed as

Cardiac Surgery ProceduresEnhanced Recovery after SurgeryPatient Blood ManagementPerioperative AnemiaValue-Based Healthcare

Identifiers

PMID41225687
PMCPMC12613330

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.