Evidence map›Paper›PMID 41225676›Full record

Observational studyJournal of ovarian research2025

Tumor recurrence risk following different COS regimens in infertile women with borderline ovarian tumors: impact on IVF outcomes.

Liang Liang, Yuan Li, Xiu-Mei Zhen, Jie Yan, Xue-Ling Song, Rong Li

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of ovarian research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liang LiangCenter for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, 100191, China.
Yuan LiCenter for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, 100191, China.
Xiu-Mei ZhenCenter for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, 100191, China.
Jie YanCenter for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, 100191, China.
Xue-Ling SongCenter for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, 100191, China. sxldxx@263.net.
Rong LiCenter for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, 100191, China.

Funding

Key Research and Development Program of Ningxia 2023BEG01001National Key Research and Development Program of China 2022YFC2703800
6 · The paper itself

Abstract

backgroundControlled ovarian stimulation (COS) is a feasible method for treating borderline ovarian tumors (BOTs) after fertility-sparing surgery (FSS). The recurrence rate does not appear to be higher in women treated with COS, and it is important to assess its effects on the pregnancy rate. There have been no reports comparing different COS regimens in patients with BOTs.

methodsThis retrospective observational study included 73 BOT patients who underwent COS. Patients were divided into two groups according to the COS regimen: the mild stimulation group (36 patients) and the agonist/antagonist cycle group (37 patients). In this study, the effects of the COS regimens on pregnancy outcomes and the risk of tumor recurrence were compared.

resultsThe follow-up time among the 73 patients was 61 (7-156) months. The proportion of patients with a serous histopathology and a micropapillary architecture was 33.3% in the mild stimulation group, which was significantly greater than that in the agonist/antagonist cycle group (P = 0.045). The initial dose of gonadotropin (Gn), the total dose of Gn, the duration of Gn treatment, and estradiol (E

conclusionE

Indexed as

Fertilization in VitroInfertility, FemaleNeoplasm Recurrence, LocalOvarian NeoplasmsOvulation InductionAdultFemaleFertility PreservationHumansPregnancyPregnancy OutcomePregnancy RateRetrospective StudiesTreatment OutcomeBorderline ovarian tumorControlled ovarian stimulationInfertilityPregnancy outcomeRecurrence

Identifiers

PMID41225676
PMCPMC12613368

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.