Evidence map›Paper›PMID 41225669›Full record

ArticleJournal of cannabis research2025

Childhood events as factors in continued cannabis use in adulthood: a longitudinal study of a 30-year follow-up cohort.

Solène Wallez, Filiz Eren, Isabelle Kousignian, Guillaume Avenin, Maria Melchior, Murielle Mary-Krause

Abstract read
In one paragraph

Article in Journal of cannabis research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Solène Wallez *Sorbonne Université, INSERM,, Institut Pierre Louis d'Epidémiologie et de Santé Publique, IPLESP, Equipe en Epidémiologie Sociale, Santé Mentale et Addictions, ESSMA, Paris, F75012, France.
Filiz Eren *Sorbonne Université, INSERM,, Institut Pierre Louis d'Epidémiologie et de Santé Publique, IPLESP, Equipe en Epidémiologie Sociale, Santé Mentale et Addictions, ESSMA, Paris, F75012, France.
Isabelle KousignianBioSTM « Biostatistique, Traitement et Modélisation des données biologiques », US25 Inserm, UAR 3612 CNRS, Faculté de Pharmacie de Paris, Université Paris Cité, Paris, F-75006, France.
Guillaume AveninSorbonne Université, Faculté de Santé Saint-Antoine, Département de Médecine Générale, Paris, 75012, France.
Maria MelchiorSorbonne Université, INSERM,, Institut Pierre Louis d'Epidémiologie et de Santé Publique, IPLESP, Equipe en Epidémiologie Sociale, Santé Mentale et Addictions, ESSMA, Paris, F75012, France.
Murielle Mary-KrauseSorbonne Université, INSERM,, Institut Pierre Louis d'Epidémiologie et de Santé Publique, IPLESP, Equipe en Epidémiologie Sociale, Santé Mentale et Addictions, ESSMA, Paris, F75012, France. murielle.mary-krause@iplesp.upmc.fr.

Funding

Institut pour la Recherche en Santé Publique TGIR CohortesMission Interministérielle de Lutte Contre les Drogues et les Conduites Addictives PIRALAD-2022
6 · The paper itself

Abstract

backgroundCannabis use patterns have evolved over time, with increasing persistence into adulthood. This study aims to identify cannabis use trajectories from adolescence to adulthood and to examine the influence of early individual and family factors on these trajectories.

methodsThis study included 622 participants from the French TEMPO cohort who reported cannabis use between 1999 and 2021, based on 14 measurements points. Cannabis consumption from adolescence to adulthood (ages 15 to 46) was assessed using Group-Based Trajectory Modelling (GBTM). Associations with early individual and family factors were examined using multinomial logistic regression.

resultsWe identified three distinct cannabis use trajectories: declining consumption (69.9%), fluctuating consumption (13.7%), characterized by an initial increase followed by a decrease, and persistent consumption (16.4%). The fluctuating use trajectory was associated with being male (OR = 2.15, 95%CI = 1.31-3.54), having parents who smoked (OR = 2.18 95%CI = 1.18-4.02), and experiencing parental conflict, stress, or frequent absence before age 17 (OR = 1.93, 95%CI = 1.15-3.23). The persistent use trajectory was associated with being male (OR = 3.66, 95%CI = 2.19-6.09), academic difficulties (OR = 2.47, 95%CI = 1.45-4.22), and early initiation of cannabis (OR = 2.31, 5%CI = 1.11-4.79) or both tobacco and cannabis (OR = 3.07, 95%CI = 1.57-6.02).

conclusionsThese findings underscore the importance of early prevention and intervention strategies, particularly in populations where cannabis use persists despite legal restrictions. Given the potential health and social consequences of prolonged cannabis use, it is essential to identify early-life risk factors to inform targeted policy measures aimed at reducing consumption and preventing cannabis use disorders.

Indexed as

Associated factorsCannabisLongitudinal studyLong-term usePredictorsTrajectory analysis

Identifiers

PMID41225669
PMCPMC12613728

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.