Evidence map›Paper›PMID 41225620›Full record

ArticleJournal of eating disorders2025

The mediating role of social connectedness between inflexibility, the suppression of emotional expression, and symptoms of eating disorders and depression in adolescents with restrictive eating disorders referred for radically open dialectical behaviour therapy (RO DBT).

Julian Baudinet, Lucinda J Gledhill, Molly Fennig Steinhoff, Kirsten Gilbert, Mima Simic

Abstract read
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Article in Journal of eating disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Julian BaudinetMaudsley Centre for Child and Adolescent Eating Disorders (MCCAED), Maudsley Hospital, De Crespigny Park, Denmark Hill, London, SE5 8AZ, UK. Julian.Baudinet@kcl.ac.uk.ORCID http://orcid.org/0000-0002-7840-4158
Lucinda J GledhillMaudsley Centre for Child and Adolescent Eating Disorders (MCCAED), Maudsley Hospital, De Crespigny Park, Denmark Hill, London, SE5 8AZ, UK.ORCID http://orcid.org/0000-0002-3288-8628
Molly Fennig SteinhoffDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.ORCID http://orcid.org/0000-0002-8402-0492
Kirsten GilbertDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.ORCID http://orcid.org/0000-0001-9367-6621
Mima SimicMaudsley Centre for Child and Adolescent Eating Disorders (MCCAED), Maudsley Hospital, De Crespigny Park, Denmark Hill, London, SE5 8AZ, UK.ORCID http://orcid.org/0000-0003-4900-1429

Funding

Neural and behavioral trajectories of the overcontrolled phenotype: Associations with development, social context and psychiatric symptoms in early childhoodR01MH126984 · NIMH · WASHINGTON UNIVERSITY · PI Kirsten Gilbert · 2022 to 2026
$3.4M
Developmental pathways and treatment of OCD and anorexia: the role heightened performance monitoring and overcontrolF31MH137979 · NIMH · WASHINGTON UNIVERSITY · PI Molly Fennig Steinhoff · 2025 to 2026
$83k
NIMH NIH HHS F31 MH137979NIMH NIH HHS R01 MH126984
6 · The paper itself

Abstract

backgroundOvercontrol is a transdiagnostic phenotype which has been associated with restrictive eating disorders and depression. It is characterised by traits such as cognitive and behavioural inflexibility, risk aversion, suppression of emotional expression, reduced reward sensitivity and higher temperamental anxiety. Two aspects of the overcontrol phenotype (inflexibility and the suppression of emotional expression) have been particularly linked with poorer mental health. Additionally, social connectedness has been shown to protect against mental health symptom severity. The current study aimed to test whether the relationship between these factors and mental health symptom severity, namely, eating disorder and depression, is mediated by social connectedness.

methodsRoutine data were collected for adolescents with restrictive eating disorders presenting to either outpatient or intensive day programme treatment in a specialist eating disorder service. Four cross-sectional mediation analyses were planned. The first two models aimed to test the mediating role of social connectedness on the relationship between inflexibility (model 1) and the suppression of emotional expression (model 2) on eating disorder symptom severity. The second two models aimed to test the mediating role of social connectedness on the relationship between inflexibility (model 3) and the suppression of emotional expression (model 4) on depression symptom severity. Baseline weight and comorbid mental health symptom severity were controlled for in each model.

resultsThe sample consisted of 109 adolescents (mean age = 15.21 years, 96.3% female). Current findings indicate that social connectedness did not statistically mediate the relationships between inflexibility and eating disorder symptom severity (model 1; Path ab β = .02, 95% bootstrap CI 0.0002-0.05). The planned analysis examining the relationship between the suppression of emotional expression and eating disorder symptoms (model 2) was not tested as the variables did not significantly correlate. Findings also indicated that social connectedness statistically mediated the relationships between both inflexibility (model 3; Path ab β = .82, 95% bootstrap CI 0.33-1.40) and the suppression of emotional expression (model 4; Path ab β = .38, 95% bootstrap CI 0.13-0 .69) on depressive symptoms.

conclusionsFindings suggest targeting social connectedness, as is the case in Radically Open Dialectical Behaviour Therapy (RO DBT), may be a useful way to improve treatment outcomes for young people with restrictive eating disorders and co-morbid depressive symptoms. This fits with qualitative data that shows that taking a holistic approach during treatment, as opposed to being overly symptom focused, is needed and valued by young people and their family members.

Indexed as

AdolescentDepressionDialectical behaviour therapyEating disordersOvercontrolRadically open dialectical behaviour therapy

Identifiers

PMID41225620
PMCPMC12613461

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.