Evidence map›Paper›PMID 41225564›Full record

ArticleBorderline personality disorder and emotion dysregulation2025

An examination of the role of PTSD and childhood trauma on treatment outcomes for individuals with borderline personality disorder in dialectical behavior therapy.

Katherine E Christensen, Shelley McMain, Alexander Chapman, Janice R Kuo

Registry-linked trialAbstract read
In one paragraph

Article in Borderline personality disorder and emotion dysregulation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02387736 (Dialectical Behaviour Therapy for Chronically Self-harming Individuals With BPD), which is not on this map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02387736 nacompletednot on this map

Dialectical Behaviour Therapy for Chronically Self-harming Individuals With BPD: Evaluating the Clinical and Cost Effectiveness of a 6-month Treatment

TypeinterventionalSponsorCentre for Addiction and Mental HealthRan2015 to 2019Enrolled240ConditionsBorderline Personality DisorderArmsDialectical Behaviour Therapy-6 months, Dialectical Behaviour Therapy-12 months
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Katherine E ChristensenPAU-Stanford PsyD Consortium, Palo Alto University, 1791 Arastradero Rd, Palo Alto, CA, CA 94304, US. kchristensen@paloaltou.edu.
Shelley McMainCenter for Addiction and Mental Health, Toronto, Canada.
Alexander ChapmanDepartment of Psychology, Simon Fraser University, Toronto, Canada.
Janice R KuoPAU-Stanford PsyD Consortium, Palo Alto University, 1791 Arastradero Rd, Palo Alto, CA, CA 94304, US.

Funding

CIHR CIHR FRN 133428
6 · The paper itself

Abstract

backgroundBorderline personality disorder (BPD) is a complex and severe mental health condition often accompanied by several co-occurring clinical problems. Posttraumatic stress disorder (PTSD) is one of the most common co-occurring disorders, with prevalence rates of PTSD reported to be between 25% and 58% among persons with BPD. The primary aim of the current study was to evaluate the association of a PTSD diagnosis and different forms of childhood trauma with changes in BPD severity, PTSD severity, and frequency of suicidal behaviors among suicidal individuals with BPD undergoing 12-months of standard dialectical behavior therapy (DBT).

methodsThis was a secondary data analysis that included individuals with BPD (N = 120) in the 12-month DBT condition. Participants completed measures of childhood abuse, PTSD severity, BPD severity, and frequency of suicidal behaviors at baseline as well as at 3, 6, 9, and 12 months. Generalized Estimating Equations (GEE) were used to examine both study hypotheses.

resultsResults suggested that the presence of PTSD did not predict reduced rates of reduction in BPD severity, PTSD severity, or frequency of suicidal behaviors. Results also revealed that higher severity of childhood sexual and emotional abuse was associated with quicker reductions in BPD severity, whereas higher severity of childhood physical abuse was associated with slower reductions. Similarly, higher severity of emotional abuse was associated with quicker reductions in PTSD severity, while higher severity of physical abuse was associated with slower reductions in this outcome.

conclusionsStandard DBT appears to be comparably effective for both individuals with BPD without PTSD and BPD + PTSD. The addition of a PTSD diagnosis did not significantly predict slower recovery among those with BPD + PTSD. In addition, different forms of childhood trauma significantly affect the trajectories of individual treatment. Our findings suggest that DBT interventions may be particularly beneficial for individuals with higher levels of emotional abuse.

trial registrationNCT02387736. Registered February 20, 2015.

Indexed as

Borderline personality disorderChildhood traumaDialectical behavior therapyPosttraumatic stress disorder

Identifiers

PMID41225564
PMCPMC12613660

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