Evidence map›Paper›PMID 41225375›Full record

ArticleBMC nephrology2025

Impact of delayed graft function on overall and graft survival in recipients of deceased donor kidney transplants.

María Andrea Negret, Martha Patricia Rodriguez, Cándida Díaz-Brochero, Santiago Abril, Santiago Grillo, Paola Garcia-Padilla

Abstract read
In one paragraph

Article in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

María Andrea NegretDepartamento de Medicina Interna, Pontificia Universidad Javeriana, Bogotá, Colombia. maria-negret@javeriana.edu.co.
Martha Patricia RodriguezDepartamento de Medicina Interna, Pontificia Universidad Javeriana, Bogotá, Colombia.
Cándida Díaz-BrocheroDepartamento de Medicina Interna, Pontificia Universidad Javeriana, Bogotá, Colombia.
Santiago AbrilDepartamento de Medicina Interna, Pontificia Universidad Javeriana, Bogotá, Colombia.
Santiago GrilloDepartamento de Medicina Interna, Pontificia Universidad Javeriana, Bogotá, Colombia.
Paola Garcia-PadillaDepartamento de Medicina Interna, Pontificia Universidad Javeriana, Bogotá, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Delayed graft function (DGF) is a frequent complication among recipients of deceased donor kidney transplants, with an incidence rate ranging from 20% to 50%. This study aimed to evaluate the impact of DGF on both graft and overall patient survival. In a retrospective cohort of 293 patients who underwent transplantation between 2007 and 2021, demographic, clinical, and long-term follow-up data were analyzed. Patients with DGF had a significantly lower 5-year graft survival rate than did those without DGF (log-rank test: p = 0.004; DGF: 80.0%, 95% CI: 70.0% − 91.0% vs. no DGF: 92.0%, 95% CI: 89.2% − 95.9%); nevertheless, without significant differences over 10 years (log-rank test: p = 0.098; DGF: 80.0%, 95% CI: 70.0% − 91.0% vs. no DGF: 87.9%, 95% CI: 83.8% − 92.1%). Regarding the overall survival, no significant differences were observed over 5 years (log-rank test: p = 0.9; DGF: 92.7%, 95% CI: 86.1% − 99.0% vs. no DGF: 92.0%, 95% CI: 89%-96%) or at 10 years (log-rank test: p = 0.81; DGF: 89.1%, 95% CI: 81.2%-97.7% vs. no DGF: 87.9%, 95% CI: 83.8%-92.1%). Multivariate analysis indicated that DGF was not associated with an increased risk of graft loss or reduced recipient survival. These findings underscore the need for larger, prospective studies to further elucidate the long-term implications of DGF and outline clinical management strategies for kidney transplant recipients.Clinical trial number Not applicable

Indexed as

Delayed Graft FunctionGraft SurvivalKidney TransplantationAdultFemaleFollow-Up StudiesHumansMaleMiddle AgedRetrospective StudiesTissue DonorsDelayed graft functionGraft lossKidney transplantsOverall survival

Identifiers

PMID41225375
PMCPMC12613648

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.