Evidence map›Paper›PMID 41225323›Full record

ReviewBMC cardiovascular disorders2025

Multidisciplinary treatment for primary cardiac angiosarcoma: a case report and overview of the literature.

Zhenzhong Wang, Shanwen Pang, Muhammad Khalid, Linbin Hua, Junqiang Qiu, Yuxin Li, Yingjie Ke, Junfei Zhao, Songxi Xie, Huanlei Huang

Abstract readCase ReportsReview
In one paragraph

Review in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhenzhong Wang *Department of Cardiac Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, P.R. China.
Shanwen Pang *Department of Cardiac Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, P.R. China.
Muhammad KhalidDepartment of Cardiac Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, P.R. China.
Linbin HuaDepartment of Cardiac Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, P.R. China.
Junqiang QiuDepartment of Cardiac Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, P.R. China.
Yuxin LiDepartment of Cardiac Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, P.R. China.
Yingjie KeDepartment of Cardiac Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, P.R. China.
Junfei ZhaoDepartment of Cardiac Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, P.R. China.
Songxi XieDepartment of Radiotherapy, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, P.R. China.
Huanlei HuangDepartment of Cardiac Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, P.R. China. hhuanlei@hotmail.com.

Funding

Guangzhou Municipal Health Commission 2023FTJCZ0011National Key Research and Development Program of China 2023YFC2307003National Natural Science Foundation of China 82270373
6 · The paper itself

Abstract

backgroundPrimary cardiac angiosarcoma is rare and highly invasive to myocardial tissue and prone to metastasis. Surgery is an effective treatment, but it is difficult and risky. Postoperative therapy could improve survival rate, but specific regimens are controversial. CASE PRESENTATION: We herein demonstrated the management experience of a patient with primary cardiac angiosarcoma at 19 weeks of pregnancy, which can be used as a reference for other patients. She underwent surgical R1 resection during pregnancy, but the fetus aborted spontaneously 4 h after surgery. Under the care of our multidisciplinary team, she also received radiotherapy, chemotherapy, and targeted therapy. After that, she was evaluated as stable disease at 14th months after surgery. She developed multiple bone metastases 16th months after surgery and finally died in the 18th month after surgery.

conclusionSurgical resection of cardiac angiosarcoma should remove as much tumor tissue as possible. Chemotherapy and targeted therapy are beneficial in shrinking tumors and control disease progression.

Indexed as

Cardiac Surgical ProceduresHeart NeoplasmsHemangiosarcomaPatient Care TeamPregnancy Complications, NeoplasticAdultBone NeoplasmsChemotherapy, AdjuvantFatal OutcomeFemaleHumansPregnancyRadiotherapy, AdjuvantTime FactorsTreatment OutcomeAngiosarcomaCardiac surgeryChemotherapyPregnancyRadiotherapyTargeted therapy

Identifiers

PMID41225323
PMCPMC12613738

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.