Evidence map›Paper›PMID 41225320›Full record

ArticleBMC plant biology2025

Integrated transcriptomic and WGCNA identify drought-responsive TFs in Larix olgensis.

Wenna Zhao, Hao Dong, Chengpeng Cui, Chen Wang, Yu Liu, Yajing Ning, Hanguo Zhang, Meng Li, Shujuan Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wenna ZhaoState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, 150040, China.
Hao DongState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, 150040, China.
Chengpeng CuiState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, 150040, China.
Chen WangState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, 150040, China.
Yu LiuState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, 150040, China.
Yajing NingState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, 150040, China.
Hanguo ZhangState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, 150040, China.
Meng LiState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, 150040, China. limeng2024@nefu.edu.cn.
Shujuan LiState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, 150040, China. lishujuan@nefu.edu.cn.

Funding

Biological Breeding-National Science and Technology Major Project 2023ZD040580204
6 · The paper itself

Abstract

Global forests face increasingly severe drought events, which suppress the growth of larch. Transcription factors (TFs), acting as regulators, can increase plant stress tolerance by modulating gene expression networks. This study integrated RNA-seq, WGCNA and physiology to systematically analyze the adaptation mechanisms of Larix olgensis under drought stress. Among the 50,110 unigenes identified via RNA-seq, 1,391 unigenes were annotated as TFs. These TFs were clustered into four distinct clusters based on expression profiles. TFs within Cluster 1 exhibited significant differential expression during visible wilting of L. olgensis (72 h and 96 h). Ten TFs were selected as candidate TFs from Cluster 1 based on fold-change rank (p < 0.05). Subsequent WGCNA clustered the 50,110 unigenes into 19 co-expression modules. Notably, the firebrick4 module displayed a strong positive correlation with hydrogen peroxide (H

Indexed as

DroughtsGene Regulatory NetworksLarixPlant ProteinsTranscription FactorsTranscriptomeGene Expression ProfilingGene Expression Regulation, PlantStress, PhysiologicalPlant ProteinsTranscription FactorsConiferGene co-expression networkModule-trait relationshipsPhysiological characteristicsRNA-seq

Identifiers

PMID41225320
PMCPMC12613604

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.