Evidence map›Paper›PMID 41225268›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Prognosis and strategies for reoperation in recurrent spinal tumors: an average 5-Year follow-up retrospective study.

Wei Gao, Zhao-Wen Gu, Qi-Xuan Jiang, Chi Gu, Jing-Yin Chen, Ai-Qin Chen, Guang-Yu Ying, Yong-Jian Zhu, Qiang-Wei Wang

Abstract read
PubMed Publisher
In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Cervical curvature changes and neurological outcomes following non-fusion surgery for cervical space-occupying lesions in adults: a multicenter retrospective study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wei GaoDepartment of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zhao-Wen GuDepartment of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Qi-Xuan JiangDepartment of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Chi GuDepartment of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Jing-Yin ChenDepartment of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Ai-Qin ChenDepartment of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Guang-Yu YingDepartment of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yong-Jian ZhuDepartment of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. neurosurgery@zju.edu.cn.
Qiang-Wei WangDepartment of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. wangqiangwei@zju.edu.cn.

Funding

National Natural Science Foundation of China 82272584National Natural Science Foundation of China 82504165
6 · The paper itself

Abstract

purposeFew studies have reported reoperation for recurrent spinal tumors. We aimed to investigate the long-term outcomes of reoperation for recurrent spinal tumors and determine the optimal surgical strategy.

methodsWe retrospectively reviewed 2000 benign spinal tumors at our center and collected patients who underwent reoperation for recurrence. Follow-up included assessment of neurological function, pain and spinal instability. Logistic regression was performed to identify prognostic factors. A web-based dynamic nomogram was constructed to quantify the risk of poor outcome.

resultsReoperation for recurrent tumors accounted for 4.1% of all spinal tumors surgeries. In this study, 94 patients who underwent reoperation were included. Long-term follow-up showed that reoperation resulted in good neurological outcomes in 72% of patients and pain improvement in 84% of patients. The recurrence rate after reoperation was 8.7%. During the reoperation, most patients (91%) did not undergo spinal internal fixation, and most patients (94%) had good spinal stability during the follow-up. We found that poor outcomes were significantly associated with longer duration of symptoms, thoracic location, longer tumor segments and meningioma. Favorable outcomes were strongly correlated with dumbbell-type tumor, complete resection, schwannoma, and good neurological function (MMS grade I/II). Regression analysis revealed that good neurological function at discharge was an independent prognostic factor. Finally, we established a preoperative nomogram to evaluate the prognosis of reoperation in recurrent tumors.

conclusionIn patients with recurrent benign spinal tumors and progressive symptoms, reoperation may improve neurological function, though outcomes vary by tumor type and location. Clinicians can use the nomogram to predict the patient subgroups that are most likely to benefit from reoperation.

Indexed as

Neoplasm Recurrence, LocalReoperationSpinal NeoplasmsAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisRetrospective StudiesTreatment OutcomeYoung AdultNomogramPrognosisRecurrenceReoperationSpinal tumors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.