ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026
Transforaminal lumbar interbody fusion (TLIF) with unilateral vs. bilateral pedicle screw fixation in iatrogenic spondylolysis: an in-vitro human cadaveric model.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTransforaminal lumbar interbody fusion (TLIF) utilizes an interbody cage augmented with pedicle screw fixation in the surgical treatment of lumbar spondylolisthesis. The current study compared the multidirectional flexibility of the lumbar spine following TLIF with unilateral (UPS) versus bilateral pedicle screw (BPS) fixation in a cadaveric pars defect model.
methodsEleven lumbosacral specimens underwent multidirectional testing (flexion-extension, FE; lateral bending, LB; axial rotation, AR) using a custom six-degree-of-freedom simulator providing unconstrained, angular displacement of 3° per second. Optoelectronic tracking at the operative (L4-L5) and adjacent levels (L3-L4, L5-S1). Seven sequential treatment conditions at the operative level were compared: intact pars, intact pars with UPS or BPS, pars defect with UPS or BPS, pars defect with TLIF and UPS or BPS. A Repeated-measures ANOVA with post hoc Bonferroni was utilized for group-to-group comparisons.
resultsBPS resulted in a significant decrease in FE, LB, and AR motion compared to UPS for the intact (FE: 3.1°, LB: 2.9°, AR: 1.7°) and pars defect conditions (FE: 3.5°, LB: 2.9°; AR: 2.5°). With the addition of TLIF, there was significant decrease in AR with BPS versus UPS (1.7°, 95% CI: 0.6–2.9).
conclusionThe biomechanical data suggest that TLIF with BPS improves axial rotational stability and should be a biomechanical consideration in the surgical management of bilateral pars defects. Clinically, this may be accomplished via traditional unilateral TLIF through a minimally invasive (MIS) approach with addition of percutaneous fixation contralaterally to preserve the characteristics of the MIS procedure while improving segmental stability of the surgical reconstruction.
Indexed as
Identifiers
41225266What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.