Evidence map›Paper›PMID 41225263›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Effects of paraspinal muscle atrophy and fatty degeneration on segmental kyphosis after conservative treatment of osteoporotic vertebral compression fracture (OVCF) in postmenopausal women.

Inwook Seo, Minjoon Cho, Taehoon Kang, Sungtaek Chung, Jae Hyup Lee

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Inwook SeoSungae Hospital, Seoul, Korea.
Minjoon ChoDepartment of Orthopedic Surgery, SMG-SNU Boramae Medical Center, 39 Boramae-ro 5-gil 20, Dongjak-gu, Seoul, 07061, Seoul, Korea.
Taehoon KangDepartment of Orthopedic Surgery, SMG-SNU Boramae Medical Center, 39 Boramae-ro 5-gil 20, Dongjak-gu, Seoul, 07061, Seoul, Korea.
Sungtaek ChungDepartment of Orthopedic Surgery, SMG-SNU Boramae Medical Center, 39 Boramae-ro 5-gil 20, Dongjak-gu, Seoul, 07061, Seoul, Korea.
Jae Hyup LeeDepartment of Orthopedic Surgery, SMG-SNU Boramae Medical Center, 39 Boramae-ro 5-gil 20, Dongjak-gu, Seoul, 07061, Seoul, Korea. spinelee@snu.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to identify factors influencing the development of segmental kyphosis development and new compression fractures in Osteoporotic Vertebral Compression Fractures (OVCF)in postmenopause women. We found fatty infiltration (FI) of the multifidus and erector spinae, high BMI, was risk of segmental kyphosis development following OVCF.

backgroundParaspinal muscles play a crucial role in maintaining sagittal balance and seem to associated with kyphosis after OVCF. However, there have been few studies investigating the factors associated with the development of segmental kyphosis development after conservative treatment OVCF in postmenopausal women. We aim to identify factors influencing the development of segmental kyphosis development after conservative treatment and the occurrence of new compression fractures.

methodsPostmenopausal women diagnosed with OVCF and managed conservatively at the author's clinic from 2012 to 2022 were retrospectively analyzed. All patients were followed up for more than 1 year and completed imaging studies. In this study, patients were divided into three groups according to the degree of segmental kyphosis development and two groups based on the presence of the newly developed compression fractures. To identify factors associated with the segmental kyphosis development and newly developed compression fractures, by comparing demographic data, radiologic data, MRI assessments, and Koval grades across the groups.

resultsA total of 200 postmenopausal women were included, with 87 in Grade 1, 78 in Grade 2, and 35 in Grade 3. Higher body mass index and higher FI in erector spinae and multifidus muscles significantly correlated with segmental kyphosis development (p-value>0.05). No significant differences in newly developed compression fractures.

conclusionHigh FI of the multifidus and erector spinae, along with high BMI, is associated with the development of segmental kyphosis development following OVCF.

Indexed as

Conservative TreatmentFractures, CompressionKyphosisMuscular AtrophyOsteoporotic FracturesParaspinal MusclesSpinal FracturesAgedAged, 80 and overFemaleHumansMiddle AgedPostmenopauseRetrospective StudiesLumbar muscularityOsteoporosisOsteoporotic vertebral compression fractureParaspinal muscleSarcopenia

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.