Trial reportClinical oral investigations2025
Effects of daily home-use water flossing as an adjunct to non-surgical periodontal therapy in the treatment of stage I-II periodontitis: a 6-month randomized controlled trial.
Trial report in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- [Current applications and future perspectives of automation technologies and devices in oral diagnosis and treatment].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2026Review
- Knowledge, awareness, and attitudes toward oral irrigator use among dentists and dental students: a cross-sectional study.BMC oral health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
objectivesTo evaluate the adjunctive effects of daily home-use water flossing alone or in combination with an herbal mouthrinse on the treatment of stage I-II periodontitis following non-surgical periodontal therapy (NSPT).
methodsThis 6-month randomized trial was performed in 72 patients with stage I-II periodontitis. These patients underwent full-mouth scaling and subgingival instrumentation and then were randomly assigned to one of three groups: control (toothbrushing), water-flossing (toothbrushing + water flossing), or water-flossing/herb-containing mouthrinse (toothbrushing + water flossing with herb-containing mouthrinse). Periodontal parameters and subgingival plaque samples were collected at baseline and at 1, 3, and 6 months. Subgingival microbiota was analyzed using 16 S rRNA sequencing.
resultsWater flossing with/without herb-containing mouthrinse resulted in a significant improvement in dental plaque index and periodontal indices. Depletion of Gemella was observed in both water-flossing groups, while the water-flossing/herb-containing mouthrinse group at 6 months showed reduced Aggregatibacter and increased Fretibacterium. Although water flossing combined with herb-containing mouthrinse further altered oral microbiota, it did not provide additional clinical improvement as compared to water flossing alone.
conclusionsDaily home-use water flossing promotes dental plaque control, reduces periodontal inflammation, and contributes to the maintenance of periodontal stability, representing an effective adjuvant measure to improve the clinical outcomes of NSPT. Additional use of herb-containing mouthrinse to water flossing offers limited incremental benefits of NSPT on periodontal health. CLINICAL SIGNIFICANCE: Water flossing is an effective adjuvant oral hygiene measure to maintain periodontal health, and additional use of herb-containing mouthrinse as an irrigant had limited incremental benefits of NSPT on periodontal health.
Indexed as
Identifiers
41225247What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.